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  • HOXB9抗体;HOXB9 Antibody—艾普蒂
  • HOXB9抗体;HOXB9 Antibody—艾普蒂
  • HOXB9抗体;HOXB9 Antibody—艾普蒂

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HOXB9抗体;HOXB9 Antibody—艾普蒂

Rabbit Polyclonal HOXB9 Antibody
询价 20μl 起订
50μl 起订
100μl 起订
上海 更新日期:2025-05-26

上海切尔齐生物科技有限公司

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联系人:周经理
电话:027-19371278702拨打
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邮箱:nuodina88@163.com

产品详情:

中文名称:
HOXB9抗体
英文名称:
Rabbit Polyclonal HOXB9 Antibody
品牌:
艾普蒂
产地:
武汉
保存条件:
Stored at -20°C for 6801 year. Avoid repeated freeze / thaw cycles.
产品类别:
抗体
重组:
应用:
WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性:
Human,Mouse,Rat
宿主:
Rabbit
偶联物:
靶点:
HOXB9

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesHOX2; HOX2E; HOX-2.5
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenSynthetic peptide of human HOXB9
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P12714(HOXB9 Antibody) at dilution 1/25. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P12714(HOXB9 Antibody) at dilution 1/25. (Original magnification: ×200)    


           

参考文献

以下是3篇关于HOXB9抗体的参考文献示例(注:文献信息为模拟虚构,仅供格式参考):

1. **文献名称**: *HOXB9 as a Prognostic Biomarker in Breast Cancer*

**作者**: Smith A, et al.

**摘要**: 研究通过HOXB9抗体免疫组化分析,发现HOXB9在乳腺癌组织中的高表达与患者生存率降低及转移风险增加显著相关,提示其作为预后标志物的潜力。

2. **文献名称**: *HOXB9 Regulates Angiogenesis in Colorectal Cancer via VEGF Signaling*

**作者**: Chen L, et al.

**摘要**: 利用HOXB9抗体进行Western blot和免疫荧光实验,证实HOXB9通过调控VEGF通路促进结直肠癌血管生成,为靶向治疗提供理论依据。

3. **文献名称**: *Epigenetic Modulation of HOXB9 in Lung Adenocarcinoma*

**作者**: Tanaka K, et al.

**摘要**: 通过HOXB9抗体结合ChIP-seq技术,揭示DNA甲基化异常导致HOXB9在肺腺癌中过表达,并促进肿瘤细胞侵袭。

4. **文献名称**: *HOXB9 Antibody-Based Therapeutic Potential in Triple-Negative Breast Cancer*

**作者**: Gupta R, et al.

**摘要**: 研究使用HOXB9中和抗体抑制三阴性乳腺癌细胞增殖,证实靶向HOXB9可降低肿瘤生长速率,具有临床转化价值。

(注:实际文献需通过PubMed/Google Scholar等平台检索关键词"HOXB9 antibody"获取。)

       

背景信息

**Background of HOXB9 Antibody**

HOXB9. a member of the Homeobox (HOX) gene family, encodes a transcription factor critical in embryonic development, particularly in establishing body patterning and tissue differentiation. HOX proteins regulate gene expression by binding to DNA, influencing cellular identity and morphogenesis. HOXB9 is notably involved in mammary gland development, hematopoiesis, and angiogenesis.

In cancer research, HOXB9 has gained attention due to its aberrant expression in malignancies like breast, lung, and colorectal cancers. Overexpression of HOXB9 is linked to tumor progression, metastasis, and therapy resistance, partly through promoting epithelial-mesenchymal transition (EMT) and angiogenesis. Its role in maintaining cancer stem cell properties further highlights its oncogenic potential.

HOXB9 antibodies are essential tools for detecting HOXB9 protein levels and localization in cells and tissues. These antibodies are widely used in techniques such as Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to study HOXB9's biological functions and mechanisms in development and disease. Researchers also employ HOXB9 antibodies to explore its prognostic value in cancers or its interaction with regulatory pathways, aiding in the identification of therapeutic targets.

Overall, HOXB9 antibodies serve as vital reagents in both basic and translational research, bridging developmental biology and oncology.

       
HOXB9抗体;HOXB9;HOXB9 Antibody;

公司简介

生物技术有限公司

成立日期 (2年)
注册资本 20万人民币
员工人数 1-10人
年营业额 ¥ 100万以内
经营模式 贸易,工厂,试剂,定制,服务
主营行业 抗体,植物生物技术,细胞培养,蛋白组学

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