EPHB1抗体;EPHB1 Antibody—艾普蒂

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     The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P12526(EPHB1 Antibody) at dilution 1/20. (Original magnification: ×200)    

  
  

**Background of EPHB1 Antibody**

The EPHB1 antibody is a tool used to detect and study EPHB1. a receptor tyrosine kinase belonging to the Eph receptor family. Eph receptors, divided into A and B subclasses based on ligand affinity, play critical roles in cell-cell communication, guiding processes like cell migration, axon guidance, and tissue patterning during development. EPHB1. a member of the B subclass, binds membrane-anchored ephrin-B ligands, triggering bidirectional signaling that regulates cell adhesion, repulsion, and spatial organization.

EPHB1 is implicated in diverse physiological and pathological contexts, including cancer progression, neurodevelopmental disorders, and vascular remodeling. In cancer, aberrant EPHB1 expression has been linked to tumor growth, metastasis, and angiogenesis in malignancies like colorectal carcinoma. In neuroscience, EPHB1 participates in synaptic plasticity and axon guidance, with potential roles in neurodegenerative diseases such as Alzheimer’s.

EPHB1 antibodies are essential for research applications like Western blotting, immunohistochemistry, and flow cytometry to localize and quantify EPHB1 expression in tissues or cells. They also facilitate functional studies, such as blocking receptor-ligand interactions to dissect signaling pathways. Both monoclonal and polyclonal EPHB1 antibodies are available, often validated for specificity and sensitivity. Recent advancements in recombinant antibody technology have improved their utility in therapeutic exploration, including targeting EPHB1 in precision oncology. Understanding EPHB1's role through antibody-based research continues to shed light on its biological significance and therapeutic potential.