CPT1C抗体;CPT1C Antibody—艾普蒂

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     The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P12503(CPT1C Antibody) at dilution 1/30. (Original magnification: ×200)    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P12503(CPT1C Antibody) at dilution 1/30. (Original magnification: ×200)    

  
  

**Background of CPT1C Antibody**

CPT1C (carnitine palmitoyltransferase 1C) is a lesser-studied isoform of the CPT1 enzyme family, which plays a critical role in fatty acid metabolism by regulating the transport of long-chain fatty acids into mitochondria for β-oxidation. Unlike CPT1A (liver isoform) and CPT1B (muscle isoform), CPT1C is primarily expressed in the brain, particularly in neurons, and is localized to the endoplasmic reticulum rather than mitochondria. Its precise biological function remains unclear, but studies suggest involvement in lipid sensing, energy homeostasis, and synaptic plasticity. CPT1C has been linked to metabolic disorders, neurodegenerative diseases, and cancer, with emerging roles in regulating cellular stress responses and tumor survival under nutrient deprivation.

CPT1C antibodies are essential tools for detecting and quantifying CPT1C protein levels in research. They enable investigations into its expression patterns, subcellular localization, and interactions in various tissues and disease models. Validated antibodies are critical due to high sequence homology among CPT1 isoforms, which can lead to cross-reactivity if not carefully characterized. Applications include Western blotting, immunohistochemistry, and immunofluorescence, aiding studies on metabolic dysregulation, brain function, and cancer biology. Recent research highlights CPT1C's potential as a therapeutic target, emphasizing the need for reliable antibodies to explore its mechanistic roles and clinical relevance.