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  • SMOC2抗体;SMOC2 Antibody—艾普蒂
  • SMOC2抗体;SMOC2 Antibody—艾普蒂
  • SMOC2抗体;SMOC2 Antibody—艾普蒂

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SMOC2抗体;SMOC2 Antibody—艾普蒂

Rabbit Polyclonal SMOC2 Antibody
询价 20μl 起订
50μl 起订
100μl 起订
上海 更新日期：2025-05-26

上海切尔齐生物科技有限公司

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联系人：周经理
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邮箱：nuodina88@163.com

产品详情:

中文名称：
SMOC2抗体
英文名称：
Rabbit Polyclonal SMOC2 Antibody
品牌：
艾普蒂
产地：
武汉
保存条件：
Stored at -20°C for 6516 year. Avoid repeated freeze / thaw cycles.
产品类别：
抗体
重组：
否
应用：
WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性：
Human,Mouse,Rat
宿主：
Rabbit
偶联物：
无
靶点：
SMOC2

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/1000-1/2000 Human,Mouse,Rat
   

产品详情

AliasesDTDP1; SMAP2; MST117; MSTP117; MSTP140; bA37D8.1; bA270C4A.1; dJ421D16.1
WB Predicted band size50 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenSynthetic peptide of human SMOC2
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human placenta tissue, Primary antibody: P12220(SMOC2 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes    


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       The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P12220(SMOC2 Antibody) at dilution 1/30. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P12220(SMOC2 Antibody) at dilution 1/30. (Original magnification: ×200)    


           

参考文献

以下是关于SMOC2抗体的3篇参考文献示例(部分信息基于假设性内容整理，实际文献需通过学术数据库验证)：

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1. **文献名称**: *"A monoclonal antibody targeting SMOC2 inhibits tumor growth in pancreatic cancer models"*

**作者**: Li, Y., et al.

**摘要**: 本研究开发了一种针对SMOC2的小鼠单克隆抗体，验证了其在胰腺癌组织中的特异性结合能力。实验表明，该抗体可通过阻断SMOC2与整合素相互作用抑制肿瘤细胞迁移和体内肿瘤生长。

2. **文献名称**: *"SMOC2 expression in cardiac fibrosis: Validation of a custom polyclonal antibody for immunohistochemistry"*

**作者**: Garcia-Ramirez, M., et al.

**摘要**: 作者制备并验证了一种兔源多克隆抗体，用于检测心脏纤维化模型中的SMOC2蛋白。抗体在免疫组化(IHC)和免疫印迹(WB)中表现出高特异性，证实SMOC2在纤维化区域显著上调。

3. **文献名称**: *"Development of a sensitive ELISA for SMOC2 detection in serum using a novel antibody pair"*

**作者**: Watanabe, K., et al.

**摘要**: 研究团队筛选出针对SMOC2不同表位的单克隆抗体，并建立了一种高灵敏度的ELISA检测方法。该抗体对能够检测血清中低浓度的SMOC2.为癌症早期诊断提供了潜在工具。

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**提示**：以上为示例性内容，实际文献需通过PubMed、Web of Science等平台检索。建议使用关键词“SMOC2 antibody”、“SMOC2 immunoassay”或结合具体应用场景(如“SMOC2 cancer”)查找近期研究。部分商业抗体的验证数据也可参考供应商网站(如Abcam、Sigma-Aldrich的产品说明书引用文献)。

       

背景信息

SMOC2 (Secreted Modular Calcium-Binding Protein 2) is a member of the SPARC (Secreted Protein Acidic and Rich in Cysteine) family, characterized by its modular structure containing follistatin-like and calcium-binding domains. It is expressed in various tissues and plays roles in extracellular matrix (ECM) organization, cell adhesion, and tissue development. SMOC2 is implicated in regulating cellular processes such as proliferation, differentiation, and angiogenesis through interactions with growth factors (e.g., BMPs) and integrin-mediated signaling pathways.

Antibodies targeting SMOC2 are essential tools for studying its expression, localization, and function in physiological and pathological contexts. They are widely used in techniques like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to detect SMOC2 in tissue samples or cell cultures. Research has linked SMOC2 overexpression to diseases such as cancer (e.g., promoting tumor progression and metastasis in colorectal, liver, and breast cancers) and fibrotic disorders (e.g., liver and lung fibrosis). Its role in embryonic development, particularly in organogenesis and tissue repair, also makes it a focus in regenerative medicine studies. SMOC2 antibodies aid in elucidating its dual roles in ECM homeostasis and disease mechanisms, offering potential as a biomarker or therapeutic target. Most commercial SMOC2 antibodies are raised against specific epitopes using recombinant proteins or synthetic peptides, validated for species reactivity (human, mouse, rat) and application-specific performance.

       
SMOC2抗体;SMOC2;SMOC2 Antibody;

公司简介

生物技术有限公司

成立日期 (2年)
注册资本 20万人民币
员工人数 1-10人
年营业额 ￥ 100万以内
经营模式 贸易,工厂,试剂,定制,服务
主营行业 抗体,植物生物技术,细胞培养,蛋白组学

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