PLXNA3抗体;PLXNA3 Antibody—艾普蒂

The PLXNA3 antibody is a research tool targeting plexin A3. a transmembrane receptor encoded by the *PLXNA3* gene. Plexins, including PLXNA3. are critical for mediating semaphorin signaling, which regulates diverse biological processes such as axon guidance, cell migration, immune response, and angiogenesis. PLXNA3 specifically interacts with class 3 semaphorins (e.g., SEMA3A, SEMA3F) and forms complexes with neuropilins or other co-receptors to transduce signals that influence cytoskeletal dynamics and cellular adhesion. Dysregulation of PLXNA3 has been implicated in neurological disorders (e.g., autism spectrum disorders, Alzheimer’s disease), cancer progression (e.g., metastasis, tumor angiogenesis), and cardiovascular diseases. The PLXNA3 antibody enables detection and localization of the protein in tissues or cells via techniques like immunohistochemistry, Western blotting, or flow cytometry. Its applications span neuroscience, oncology, and immunology, aiding in elucidating PLXNA3's roles in disease mechanisms and potential therapeutic targeting. Recent studies also explore its involvement in synaptic plasticity and immune modulation, highlighting its multifaceted importance in cellular communication and pathophysiology.