C12orf75抗体;C12orf75 Antibody—艾普蒂

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     The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P12005(C12orf75 Antibody) at dilution 1/20. (Original magnification: ×200)    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human brain  tissue using P12005(C12orf75 Antibody) at dilution 1/20. (Original magnification: ×200)    

  
  

The C12orf75 antibody is a research tool designed to detect the protein encoded by the *C12orf75* gene (Chromosome 12 Open Reading Frame 75), also known as *CABLES2*. This gene is conserved across vertebrates, but its precise biological function remains incompletely characterized. Studies suggest C12orf75 may play roles in cellular processes such as apoptosis, cell cycle regulation, or signal transduction, with potential links to cancer and neurological disorders. The protein is predicted to localize to the cytoplasm and nucleus, though its expression patterns vary across tissues.

C12orf75 antibodies are commonly used in techniques like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to study protein expression, subcellular localization, and interactions. Commercial antibodies are typically raised in hosts like rabbits or mice, using immunogens derived from synthetic peptides or recombinant protein fragments. Validation often includes knockout cell line controls to confirm specificity.

Research interest in C12orf75 has grown due to its reported dysregulation in diseases. For example, altered expression has been observed in certain cancers, suggesting potential diagnostic or therapeutic relevance. However, functional studies remain limited, and further investigation is needed to clarify its molecular mechanisms. The availability of C12orf75 antibodies supports ongoing efforts to explore its role in health and disease, bridging gaps in understanding this understudied gene.