FAM13B抗体;FAM13B Antibody—艾普蒂

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     The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P11756(FAM13B Antibody) at dilution 1/30. (Original magnification: ×200)    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P11756(FAM13B Antibody) at dilution 1/30. (Original magnification: ×200)    

  
  

**Background of FAM13B Antibody**

The FAM13B (Family with Sequence Similarity 13 Member B) antibody is a tool used to detect and study the FAM13B protein, a member of the FAM13 family implicated in diverse cellular processes. Although the precise biological role of FAM13B remains under investigation, it shares structural homology with other FAM13 proteins, which are linked to metabolic regulation, cell signaling, and disease pathways. FAM13B is hypothesized to interact with components of the Wnt/β-catenin signaling pathway, suggesting potential roles in cellular differentiation or proliferation.

Research using FAM13B antibodies has revealed its expression in tissues such as the brain, lungs, and reproductive organs, with variations observed in certain cancers and metabolic disorders. These antibodies, often produced in rabbits or mice (polyclonal or monoclonal), are validated for applications like Western blotting, immunohistochemistry, and immunofluorescence to assess protein expression, localization, and post-translational modifications.

Interest in FAM13B stems from its association with diseases like chronic obstructive pulmonary disease (COPD) and cancer, where altered expression may serve as a biomarker or therapeutic target. Studies also explore its interaction with hypoxia-inducible factors or lipid metabolism regulators, highlighting its potential cross-talk with stress-response pathways. However, further functional studies are needed to clarify its mechanistic contributions to physiology and pathology.