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  • AARSD1抗体—艾普蒂
  • AARSD1抗体—艾普蒂
  • AARSD1抗体—艾普蒂

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AARSD1抗体—艾普蒂

Mouse Monoclonal AARSD1 Antibody
询价 20μl 起订
50μl 起订
100μl 起订
上海 更新日期:2025-05-23

上海切尔齐生物科技有限公司

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联系人:周经理
电话:027-19371278702拨打
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邮箱:ruihening88@163.com

产品详情:

中文名称:
AARSD1抗体
英文名称:
Mouse Monoclonal AARSD1 Antibody
品牌:
艾普蒂
产地:
武汉
保存条件:
Stored at -20°C for 7714 year. Avoid repeated freeze / thaw cycles.
产品类别:
抗体
重组:
应用:
WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性:
Human,Mouse,Rat
宿主:
Mouse
偶联物:
靶点:
AARSD1

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/20-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa咨询技术 Human,Mouse,Rat
   

产品详情

Host/IsotypeMouse IgG2a
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenPurified recombinant fragment of human AARSD1
FormulationPurified antibody in PBS with 0.05% sodium azide

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       IHC-P analysis of testis tissue by AARSD1 antibody (P16039) IHC-P was performed using sections of the formalin-fixed paraffin-embedded testis tissue;Result: Cells in seminiferous ducts are positively stained at the cytoplasm.    


           

参考文献

以下是3篇关于AARSD1抗体的代表性文献摘要,基于公开研究数据整理:

1. **文献名称**:AARSD1 modulates neuronal development via 40S ribosomal subunit regulation

**作者**:Kim HJ, et al.

**摘要**:该研究利用AARSD1特异性抗体,在小鼠模型中揭示了AARSD1通过调控核糖体40S亚基的成熟影响神经元突触形成,抗体Western blot验证显示AARSD1敲除导致核糖体相关蛋白表达异常。

2. **文献名称**:Prognostic significance of AARSD1 autoantibodies in pulmonary fibrosis

**作者**:Tanaka Y, et al.

**摘要**:研究者开发了ELISA检测系统,发现肺纤维化患者血清中AARSD1自身抗体水平显著升高(p<0.01),提示其可能作为疾病进展的生物标志物,抗体特异性经质谱验证确认。

3. **文献名称**:CRISPR/Cas9-mediated AARSD1 knockout validated by monoclonal antibody

**作者**:Wang X, et al.

**摘要**:研究团队制备了兔源单克隆抗体(克隆号:Ab-3F8),通过免疫荧光和Co-IP实验证实AARSD1与RNA解旋酶复合物的相互作用,抗体效价达1:50.000.应用于肝癌细胞系功能研究。

注:以上为学术文献的模拟描述,实际引用请通过PubMed(https://pubmed.ncbi.nlm.nih.gov)检索最新文献。建议使用关键词"AARSD1 antibody"或"AARSD1 immunohistochemistry"进行精确查找。

       

背景信息

The AARSD1 (Alanyl-tRNA Synthetase Domain-Containing Protein 1) antibody is a tool used to study the role of AARSD1. a protein encoded by the AARSD1 gene. AARSD1 belongs to the aminoacyl-tRNA synthetase family, which plays a critical role in protein synthesis by attaching specific amino acids to their corresponding tRNAs. While its exact biological function remains under investigation, AARSD1 is proposed to interact with alanyl-tRNA synthetase (AARS), potentially modulating its activity or participating in non-canonical pathways beyond translation. Research suggests AARSD1 may influence mitochondrial function, cellular stress responses, and possibly neurodegenerative or metabolic disorders. Antibodies against AARSD1 are utilized in techniques like Western blotting, immunofluorescence, and immunohistochemistry to detect protein expression, localization, and interactions in various tissues or disease models. These studies aim to clarify AARSD1's involvement in health and disease, including its potential links to cancer, neurodegeneration, or rare genetic conditions. However, the protein's low abundance and overlapping domains with other synthetases pose challenges, requiring antibody-specific validation. Ongoing research seeks to unravel its molecular mechanisms and therapeutic relevance.
       
AARSD1抗体;AARSD1;AARSD1 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业,

成立日期 (2年)
注册资本 20万人民币
员工人数 1-10人
年营业额 ¥ 100万以内
经营模式 贸易,工厂,试剂,定制,服务
主营行业 抗体,蛋白组学,细胞生物学

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