ANKRD26P1抗体—艾普蒂 新品

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     IHC-P analysis of testis tissue by ANKRD26P1 antibody (P16038) IHC-P was performed using sections of the formalin-fixed paraffin-embedded testis tissue;Result: Cells in seminiferous ducts are positively stained at the acrosome.    

  
  

**Background of ANKRD26P1 Antibody**

ANKRD26P1 (Ankyrin Repeat Domain 26 Pseudogene 1) is a pseudogene derived from the protein-coding gene ANKRD26. located on chromosome 10p12.1. Pseudogenes, once considered non-functional genomic relics, are now recognized for potential regulatory roles in gene expression, acting through mechanisms like non-coding RNA interactions or chromatin modulation. ANKRD26P1 retains sequence homology with ANKRD26. a gene implicated in hematopoiesis and thrombopoiesis, but lacks functional protein-coding capacity due to evolutionary mutations.

Antibodies targeting ANKRD26P1 are primarily used in research to study its expression patterns and regulatory functions. Though ANKRD26P1’s biological significance remains under investigation, it has been observed in contexts such as cancer and hematopoietic disorders. For instance, dysregulation of ANKRD26-related pathways is linked to myeloid malignancies and platelet disorders, suggesting ANKRD26P1 might influence these processes via competitive endogenous RNA (ceRNA) activity or epigenetic interactions.

ANKRD26P1 antibodies enable detection in techniques like immunohistochemistry, Western blotting, or RNA-protein interaction assays, aiding exploration of its role in cellular homeostasis, disease mechanisms, or as a biomarker. Research focuses on elucidating its interplay with ANKRD26 and other genes, potentially uncovering novel therapeutic targets in hematologic cancers or genetic syndromes associated with ANKRD26 dysfunction.