FOXD2抗体—艾普蒂

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     The image is immunohistochemistry of paraffin-embedded Human brain cancer tissue using P10860(FOXD2 Antibody) at dilution 1/25. (Original magnification: ×200)    

  
  

The FOXD2 antibody is designed to target FOXD2. a member of the Forkhead box (FOX) family of transcription factors, which are characterized by a conserved DNA-binding domain known as the "forkhead box." FOXD2 plays critical roles in embryonic development, cellular differentiation, and tissue homeostasis. It regulates gene expression by binding to specific DNA sequences, influencing pathways involved in cell proliferation, apoptosis, and migration. Dysregulation of FOXD2 has been implicated in various cancers, including colorectal, breast, and ovarian cancers, where it may act as either an oncogene or tumor suppressor depending on the cellular context. For instance, FOXD2 overexpression has been linked to enhanced tumor invasiveness in certain malignancies, while its loss is associated with poor prognosis in others.

FOXD2 antibodies are essential tools for studying the protein's expression, localization, and function. They are widely used in techniques like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to detect FOXD2 in cell lines, tissues, or clinical samples. Validated antibodies help researchers explore FOXD2's role in disease mechanisms, its interaction partners, and its potential as a therapeutic target. Many commercially available FOXD2 antibodies are raised against specific epitopes within the protein and are tested for specificity using knockout controls or siRNA-mediated silencing. As research advances, FOXD2 antibodies continue to support investigations into developmental disorders, cancer biology, and regenerative medicine, highlighting their importance in both basic and translational studies.