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  • KRT16抗体—艾普蒂
  • KRT16抗体—艾普蒂
  • KRT16抗体—艾普蒂

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KRT16抗体—艾普蒂

Rabbit Polyclonal KRT16 Antibody
询价 20μl 起订
50μl 起订
100μl 起订
上海 更新日期：2025-05-21

上海切尔齐生物科技有限公司

VIP1年
联系人：周经理
电话：027-19371278702拨打
手机：18008634902 拨打
邮箱：ruihening88@163.com

产品详情:

中文名称：
KRT16抗体
英文名称：
Rabbit Polyclonal KRT16 Antibody
品牌：
艾普蒂
产地：
武汉
保存条件：
Stored at -20°C for 5717 year. Avoid repeated freeze / thaw cycles.
产品类别：
抗体
重组：
否
应用：
WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性：
Human,Mouse,Rat
宿主：
Rabbit
偶联物：
无
靶点：
KRT16

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

产品详情

AliasesK16; CK16; K1CP; NEPPK; FNEPPK; KRT16A
WB Predicted band size51 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenSynthetic peptide of human KRT16
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Hela cells, Primary antibody: P10758(KRT16 Antibody) at dilution 1/450, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P10758(KRT16 Antibody) at dilution 1/30. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P10758(KRT16 Antibody) at dilution 1/30. (Original magnification: ×200)    


           

参考文献

以下是模拟生成的3篇关于KRT16抗体的参考文献示例(实际文献需通过学术数据库验证)：

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1. **文献名称**：*KRT16 Expression in Psoriatic Epidermis: A Marker of Hyperproliferation*

**作者**：Smith J, et al.

**摘要**：本研究利用特异性KRT16抗体进行免疫组化分析，发现银屑病患者表皮中KRT16显著上调，与角质形成细胞异常增殖相关，提示其作为银屑病病理生物标志物的潜力。

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2. **文献名称**：*Development of a Monoclonal Antibody Against Human KRT16 for Cancer Diagnostics*

**作者**：Lee H, et al.

**摘要**：报道了一种新型抗人KRT16单克隆抗体的开发与验证。该抗体在胰腺癌和口腔鳞状细胞癌组织中表现出高特异性，可用于区分恶性与正常上皮组织。

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3. **文献名称**：*KRT16 Antibody Reveals Dynamic Expression During Wound Healing*

**作者**：Garcia R, et al.

**摘要**：通过KRT16抗体追踪小鼠皮肤伤口愈合过程，发现KRT16在修复早期阶段短暂高表达，可能与上皮迁移和屏障功能重建相关。

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**注**：以上内容为示例，实际文献请通过 **PubMed/Google Scholar** 检索关键词如 "KRT16 antibody" 或 "anti-KRT16 application" 获取。部分真实研究可能涉及：

- KRT16在炎症性皮肤病、癌症及伤口修复中的功能

- 抗体在诊断或机制研究中的技术应用(如Western blot、IHC)

       

背景信息

Keratin 16 (KRT16) is a type I intermediate filament protein encoded by the *KRT16* gene, primarily expressed in stratified epithelia, including the skin, nails, and mucosal tissues. It plays a critical role in maintaining epithelial integrity, cell proliferation, and stress response. KRT16 is often co-expressed with KRT6 in hyperproliferative or damaged epithelia, forming a heterodimer that stabilizes the cytoskeleton during tissue repair or inflammation. Dysregulation of KRT16 is linked to pathological conditions such as psoriasis, eczema, and pachyonychia congenita (a genetic disorder causing thickened nails and palmoplantar keratoderma). It is also implicated in tumorigenesis, particularly in squamous cell carcinomas and certain adenocarcinomas.

KRT16 antibodies are essential tools for detecting this protein in research and diagnostics. They are widely used in immunohistochemistry (IHC), immunofluorescence (IF), and Western blotting to study its expression patterns in normal vs. diseased tissues. Commercially available antibodies target specific epitopes, enabling precise localization and quantification. Recent studies explore KRT16's role in immune modulation, wound healing, and cancer metastasis, highlighting its potential as a biomarker or therapeutic target. Validation of KRT16 antibodies ensures specificity and reproducibility, crucial for advancing understanding of epithelial biology and associated disorders.

       
KRT16抗体;KRT16;KRT16 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业，

成立日期 (2年)
注册资本 20万人民币
员工人数 1-10人
年营业额 ￥ 100万以内
经营模式 贸易,工厂,试剂,定制,服务
主营行业 抗体,蛋白组学,细胞生物学

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