OXSM抗体—艾普蒂 新品

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     Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Hela cell lysate, Primary antibody: P10532(OXSM Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 30 seconds    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P10532(OXSM Antibody) at dilution 1/130. (Original magnification: ×200)    

  
  

OXSM (Oxysterol-binding protein-related protein 7. ORP7) is a member of the OSBP-related protein family, which is involved in lipid metabolism, intracellular membrane trafficking, and cell signaling. These proteins typically contain a conserved oxysterol-binding domain (OSBP-related domain, ORD) that binds oxysterols, cholesterol, or phospholipids, enabling their role as lipid sensors or transporters. OXSM is particularly associated with regulating lipid distribution between cellular membranes, such as the endoplasmic reticulum (ER) and Golgi apparatus, and may influence membrane contact site dynamics. Dysregulation of OXSM has been implicated in metabolic disorders, neurodegenerative diseases, and cancers due to its impact on lipid homeostasis and signaling pathways.

OXSM antibodies are essential tools for detecting and quantifying OXSM protein expression in research. They are widely used in techniques like Western blotting, immunofluorescence, and immunohistochemistry to study OXSM localization, interaction partners, and expression patterns in various tissues or disease models. Such studies help elucidate OXSM’s role in lipid-mediated processes, including apoptosis, autophagy, and vesicular transport. Additionally, OXSM antibodies contribute to exploring its potential as a biomarker or therapeutic target in conditions linked to lipid dysregulation, such as atherosclerosis or liver disease.

Overall, OXSM antibodies advance our understanding of lipid-centric cellular mechanisms and their pathological implications.