H4C1抗体—艾普蒂

The H4C1 antibody specifically targets histone H4. a core component of nucleosomes that package DNA into chromatin. Histone H4. encoded by multiple genes (e.g., H4C1. H4C2), plays a critical role in maintaining chromatin structure and regulating gene expression through post-translational modifications (e.g., acetylation, methylation). As a highly conserved protein, H4 is essential for DNA replication, repair, and epigenetic regulation. The H4C1 antibody is commonly used in epigenetics research to investigate histone modification patterns, chromatin dynamics, and their roles in cellular processes like transcription and genome stability. It is widely applied in techniques such as chromatin immunoprecipitation (ChIP), Western blotting, and immunofluorescence. Commercial H4C1 antibodies are typically raised against synthetic peptides corresponding to conserved regions of human H4 and are validated for specificity across species. Its utility extends to studying diseases linked to chromatin dysregulation, including cancer and developmental disorders. Researchers rely on H4C1 antibodies to explore histone variant functions, nucleosome remodeling, and the interplay between histone modifications and cellular signaling pathways.