GAN抗体—艾普蒂

Generative Adversarial Network (GAN) antibodies refer to synthetic antibodies designed using GANs, a class of machine learning frameworks. GANs consist of two neural networks—a generator and a discriminator—that compete to improve accuracy. In antibody development, this approach leverages GANs to model and optimize antibody structures, particularly for targeting specific antigens. Traditional antibody discovery relies on experimental methods like phage display or hybridoma technology, which are time-consuming and costly. GANs offer a computational alternative by predicting antibody-antigen interactions and generating novel antibody sequences with desired properties, such as high affinity or stability. This innovation accelerates drug discovery, especially for diseases with rapidly evolving pathogens (e.g., COVID-19) or complex targets like cancer. However, challenges remain, including ensuring generated antibodies are biologically feasible and compatible with manufacturing processes. Integrating GANs with experimental validation and structural biology tools may bridge this gap, enabling data-driven, high-throughput antibody design. The fusion of AI and biotechnology in this field holds promise for personalized medicine and addressing unmet therapeutic needs.