GDPD2抗体—艾普蒂

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     Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: HepG2 cell lysate, Primary antibody: P10450(GDPD2 Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 30 seconds    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using P10450(GDPD2 Antibody) at dilution 1/105. (Original magnification: ×200)    

  
  

The GDPD2 (Glycerophosphodiester Phosphodiesterase Domain-Containing Protein 2) antibody is a tool used to study the GDPD2 protein, which belongs to the glycerophosphodiester phosphodiesterase (GDPD) family. This enzyme hydrolyzes glycerophosphodiesters to produce glycerol phosphate and alcohols, playing a role in lipid metabolism and cellular signaling. GDPD2 is implicated in maintaining membrane homeostasis and regulating bioactive lipid mediators, such as lysophosphatidic acid (LPA), which influence cell proliferation, differentiation, and apoptosis.

Research on GDPD2 has linked it to metabolic disorders, cancer, and immune regulation. For instance, altered GDPD2 expression has been observed in certain tumors, suggesting its potential as a biomarker or therapeutic target. The GDPD2 antibody enables detection and quantification of the protein in tissues or cell lines via techniques like Western blot, immunohistochemistry (IHC), and immunofluorescence (IF). It is critical for investigating GDPD2's physiological functions, subcellular localization, and interaction networks.

Commercial GDPD2 antibodies are typically raised in hosts like rabbits or mice using immunogenic peptide sequences. Validation includes specificity tests (knockout controls) and application-specific performance checks. Despite its niche focus, this antibody supports broader studies in lipidomics, cancer biology, and metabolic disease mechanisms.