C11orf54抗体—艾普蒂

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     Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: HepG2 cell lysate, Primary antibody: P10349(C11orf54 Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 2 minutes    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P10349(C11orf54 Antibody) at dilution 1/50. (Original magnification: ×200)    

  
  

The C11orf54 antibody targets the protein encoded by the chromosome 11 open reading frame 54 (C11orf54) gene, a locus with limited functional characterization in current scientific literature. This gene, also referred to as "FAM237A" or "UPF0690." is annotated as a putative transmembrane protein, though its precise biological role remains unclear. Emerging studies suggest potential involvement in cellular signaling pathways or protein-protein interactions, particularly in neural or secretory systems, but these associations require further validation.

C11orf54 antibodies are primarily utilized as research tools to investigate the protein's expression patterns, subcellular localization, and potential disease correlations. Commercial antibodies are typically polyclonal or monoclonal preparations validated for applications like Western blotting, immunohistochemistry, or immunofluorescence. Recent exploratory studies have reported altered C11orf54 expression in certain cancers (e.g., gliomas, pancreatic tumors) and neurological disorders, sparking interest in its biomarker potential. However, interpretation of results requires caution due to limited antibody validation data and unresolved questions regarding protein isoforms or post-translational modifications.

Ongoing research aims to elucidate C11orf54's physiological functions and pathological relevance, with corresponding antibodies serving as critical reagents for these exploratory investigations. Standardization of antibody validation protocols remains essential to ensure experimental reproducibility in this emerging field.