CCDC134抗体—艾普蒂

The CCDC134 (coiled-coil domain-containing protein 134) antibody is a research tool developed to study the function and expression of the CCDC134 protein, a member of the coiled-coil domain-containing protein family. CCDC134 is implicated in regulating immune responses and cellular signaling pathways. Early studies suggest it acts as a cytokine-like factor, influencing T-cell activation and differentiation, and may play roles in autoimmune diseases and cancer progression. Its involvement in modulating the MAPK/ERK signaling pathway highlights its potential impact on cell proliferation and apoptosis. The antibody, typically generated in hosts like rabbits or mice using immunogenic peptide fragments or recombinant proteins, enables detection of CCDC134 in techniques such as Western blotting, immunohistochemistry, and flow cytometry. Validation often includes testing in cell lines or tissues with confirmed CCDC134 expression and assessing cross-reactivity. Researchers utilize this antibody to explore CCDC134's role in tumor microenvironments, immune evasion mechanisms, and therapeutic targeting. Its development addresses the need for reliable tools to decipher CCDC134's biological significance, offering insights into its diagnostic or therapeutic potential in diseases like hepatocellular carcinoma and rheumatoid arthritis.