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网站主页 MRPS28 antibody MRPS28抗体
  • MRPS28抗体—艾普蒂
  • MRPS28抗体—艾普蒂
  • MRPS28抗体—艾普蒂

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MRPS28抗体—艾普蒂

Rabbit Polyclonal MRPS28 Antibody
询价 20μl 起订
50μl 起订
100μl 起订
上海 更新日期：2025-05-21

上海切尔齐生物科技有限公司

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联系人：周经理
电话：027-19371278702拨打
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邮箱：ruihening88@163.com

产品详情:

中文名称：
MRPS28抗体
英文名称：
Rabbit Polyclonal MRPS28 Antibody
品牌：
艾普蒂
产地：
武汉
保存条件：
Stored at -20°C for 5414 year. Avoid repeated freeze / thaw cycles.
产品类别：
抗体
重组：
否
应用：
WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性：
Human,Mouse,Rat
宿主：
Rabbit
偶联物：
无
靶点：
MRPS28

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesMRPS35; HSPC007; MRP-S28; MRP-S35
WB Predicted band size21 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenFusion protein of human MRPS28
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: HL-60 cell lysate, Primary antibody: P10283(MRPS28 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 15 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P10283(MRPS28 Antibody) at dilution 1/60. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P10283(MRPS28 Antibody) at dilution 1/60. (Original magnification: ×200)    


           

参考文献

以下是关于MRPS28抗体的3篇参考文献示例(注：以下内容为模拟虚构，仅供参考格式)：

1. **文献名称**: *Mitochondrial ribosomal protein S28 antibody validation in hepatocellular carcinoma*

**作者**: Wang, L. et al.

**摘要**: 本研究验证了一种高特异性的MRPS28多克隆抗体，通过免疫印迹和免疫组化技术，发现MRPS28在肝癌组织中的表达显著高于正常肝组织，提示其可能作为肝癌诊断的潜在生物标志物。

2. **文献名称**: *Role of MRPS28 in mitochondrial dysfunction: Insights from antibody-based knockdown assays*

**作者**: Gonzalez, S. & Patel, R.

**摘要**: 利用MRPS28抗体进行蛋白质敲低实验，发现MRPS28缺失会导致线粒体呼吸链复合物活性下降，表明其在维持线粒体功能中起关键作用，并与神经退行性疾病相关。

3. **文献名称**: *Development of a monoclonal antibody against MRPS28 for mitochondrial proteomics studies*

**作者**: Kim, J. et al.

**摘要**: 报道了一种新型MRPS28单克隆抗体的开发，通过质谱和免疫荧光验证其特异性，并应用于线粒体蛋白质组学分析，揭示了MRPS28在不同细胞类型中的亚定位差异。

(注：若需真实文献，建议通过PubMed或Google Scholar以“MRPS28 antibody”为关键词检索。)

       

背景信息

The MRPS28 antibody is a tool used to detect mitochondrial ribosomal protein S28 (MRPS28), a component of the small subunit (28S) of the mitochondrial ribosome. Mitochondrial ribosomes are essential for translating mitochondrial DNA-encoded mRNAs, producing proteins critical for oxidative phosphorylation (OXPHOS) and cellular energy metabolism. MRPS28 plays a structural or functional role in ribosome assembly, ensuring proper synthesis of electron transport chain (ETC) complexes. Dysregulation of mitochondrial ribosomal proteins, including MRPS28. is linked to mitochondrial disorders, cancer, and neurodegenerative diseases.

Antibodies against MRPS28 enable researchers to study its expression, localization, and interactions via techniques like Western blotting, immunofluorescence, and immunohistochemistry. These studies help elucidate its role in mitochondrial dysfunction and disease mechanisms. For example, reduced MRPS28 levels may impair mitochondrial translation, leading to ETC deficiencies and metabolic stress. In cancer, altered MRPS28 expression has been observed in certain tumors, suggesting potential as a biomarker or therapeutic target.

Commercial MRPS28 antibodies are typically validated for specificity across human and model organisms, supporting research in mitochondrial biology and pathology. Understanding MRPS28's function contributes to insights into cellular energy regulation and disease pathways involving mitochondrial protein synthesis.

       
MRPS28抗体;MRPS28;MRPS28 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业，

成立日期 (2年)
注册资本 20万人民币
员工人数 1-10人
年营业额 ￥ 100万以内
经营模式 贸易,工厂,试剂,定制,服务
主营行业 抗体,蛋白组学,细胞生物学

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