RPS16抗体—艾普蒂

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     The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P10252(RPS16 Antibody) at dilution 1/60. (Original magnification: ×200)    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P10252(RPS16 Antibody) at dilution 1/60. (Original magnification: ×200)    

  
  

The ribosomal protein S16 (RPS16) antibody is a tool used to detect and study the RPS16 protein, a component of the 40S ribosomal subunit involved in protein synthesis. RPS16 plays a critical role in ribosome biogenesis, facilitating rRNA processing and ribosome assembly. Dysregulation of RPS16 has been linked to cellular stress responses, cell cycle control, and apoptosis, with implications in diseases such as cancer and Diamond-Blackfan anemia (DBA), a rare genetic disorder characterized by ribosomal dysfunction.

The RPS16 antibody is widely utilized in research to investigate protein expression, localization, and interactions via techniques like Western blotting, immunofluorescence, and immunohistochemistry. It helps elucidate RPS16's role in pathological conditions, including tumorigenesis, where altered ribosome dynamics may promote cancer progression. Additionally, studies suggest RPS16 may serve as a biomarker or therapeutic target in certain malignancies. Commercial RPS16 antibodies are typically validated for specificity across human, mouse, and rat samples, supporting cross-species research. Ongoing studies focus on understanding its extra-ribosomal functions, such as modulating signaling pathways independent of protein synthesis, highlighting its broader biological significance.