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  • RPL35抗体—艾普蒂
  • RPL35抗体—艾普蒂
  • RPL35抗体—艾普蒂

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RPL35抗体—艾普蒂

Rabbit Polyclonal RPL35 Antibody
询价 20μl 起订
50μl 起订
100μl 起订
上海 更新日期:2025-05-21

上海切尔齐生物科技有限公司

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产品详情:

中文名称:
RPL35抗体
英文名称:
Rabbit Polyclonal RPL35 Antibody
品牌:
艾普蒂
产地:
武汉
保存条件:
Stored at -20°C for 5378 year. Avoid repeated freeze / thaw cycles.
产品类别:
抗体
重组:
应用:
WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性:
Human,Mouse,Rat
宿主:
Rabbit
偶联物:
靶点:
RPL35

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesL35
WB Predicted band size15 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human RPL35
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: Jurkat cell lysate, Primary antibody: P10234(RPL35 Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 90 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using P10234(RPL35 Antibody) at dilution 1/70. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P10234(RPL35 Antibody) at dilution 1/70. (Original magnification: ×200)    


           

参考文献

以下是关于RPL35抗体的模拟参考文献示例(仅供参考,实际文献需通过学术数据库检索):

1. **"RPL35 as a novel biomarker in hepatocellular carcinoma: Expression analysis and clinical significance"**

- 作者:Li X, et al.

- 摘要:研究通过免疫组化(使用RPL35特异性抗体)检测肝细胞癌组织中RPL35的表达水平,发现其高表达与患者预后不良相关,提示RPL35可能作为肝癌治疗的潜在靶点。

2. **"Role of RPL35 in regulating cell cycle progression via p53 signaling pathway"**

- 作者:Wang Y, et al.

- 摘要:利用RPL35抗体进行Western blot和免疫荧光实验,证明RPL35通过调控p53通路影响细胞周期停滞,敲低RPL35导致癌细胞增殖抑制。

3. **"Development and validation of a high-specificity monoclonal antibody for human RPL35"**

- 作者:Zhang H, et al.

- 摘要:报道了一种新型RPL35单克隆抗体的制备与验证,通过ELISA、免疫印迹和免疫沉淀实验证实其高特异性和灵敏度,为后续研究提供工具。

4. **"RPL35 modulates ribosome biogenesis and promotes colorectal cancer metastasis"**

- 作者:Chen J, et al.

- 摘要:研究通过RPL35抗体检测发现,RPL35在结直肠癌转移灶中表达显著升高,机制上通过促进核糖体生物合成驱动肿瘤侵袭转移。

(注:以上为模拟生成的参考文献,实际引用请以真实文献为准。)

       

背景信息

The RPL35 antibody is a crucial tool for studying ribosomal protein L35 (RPL35), a component of the 60S large ribosomal subunit involved in protein synthesis. RPL35. encoded by the RPL35 gene, plays a role in ribosome assembly and translational fidelity. Dysregulation of RPL35 has been linked to various diseases, including cancers (e.g., hepatocellular carcinoma, colorectal cancer) and ribosomopathies, highlighting its importance in cellular homeostasis. The antibody specifically detects RPL35 in applications like Western blotting, immunohistochemistry, and immunofluorescence, enabling researchers to analyze its expression, localization, and interactions. Its utility extends to investigating ribosomal stress responses, cancer progression mechanisms, and potential therapeutic targets. Commercially available RPL35 antibodies are typically produced in hosts like rabbits or mice, targeting specific epitopes with validated specificity. Recent studies also explore its role in viral infections, where ribosomal proteins may influence pathogen replication. By facilitating precise detection, the RPL35 antibody supports advancements in understanding ribosome biology and disease pathology, bridging basic research and clinical applications.
       
RPL35抗体;RPL35;RPL35 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业,

成立日期 (2年)
注册资本 20万人民币
员工人数 1-10人
年营业额 ¥ 100万以内
经营模式 贸易,工厂,试剂,定制,服务
主营行业 抗体,蛋白组学,细胞生物学

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