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  • TMEM141抗体—艾普蒂
  • TMEM141抗体—艾普蒂
  • TMEM141抗体—艾普蒂

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TMEM141抗体—艾普蒂

Rabbit Polyclonal TMEM141 Antibody
询价 20μl 起订
50μl 起订
100μl 起订
上海 更新日期:2025-05-21

上海切尔齐生物科技有限公司

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邮箱:ruihening88@163.com

产品详情:

中文名称:
TMEM141抗体
英文名称:
Rabbit Polyclonal TMEM141 Antibody
品牌:
艾普蒂
产地:
武汉
保存条件:
Stored at -20°C for 5373 year. Avoid repeated freeze / thaw cycles.
产品类别:
抗体
重组:
应用:
WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性:
Human,Mouse,Rat
宿主:
Rabbit
偶联物:
靶点:
TMEM141

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/40-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

WB Predicted band size12 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenFusion protein of human TMEM141
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal liver tissue lysate, Primary antibody: P10226(TMEM141 Antibody) at dilution 1/900, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 2 minutes    


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       The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P10226(TMEM141 Antibody) at dilution 1/60. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P10226(TMEM141 Antibody) at dilution 1/60. (Original magnification: ×200)    


           

参考文献

以下是假设性的示例参考文献,用于说明可能的文献结构和内容(实际文献需通过学术数据库验证):

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1. **文献名称**: *TMEM141 regulates neuronal development and autism-associated behaviors*

**作者**: Smith J, et al. (2018)

**摘要**: 研究报道了TMEM141蛋白在小鼠前脑神经元发育中的关键作用,并通过抗体定位实验揭示其与突触形成相关。基因缺失模型显示自闭症样行为,提示TMEM141可能是神经发育障碍的潜在靶点。

2. **文献名称**: *Antibody-based profiling of TMEM141 in cellular stress response*

**作者**: Zhang L, et al. (2020)

**摘要**: 利用特异性抗体研究TMEM141在氧化应激中的表达变化,发现其通过调控线粒体膜稳定性参与细胞凋亡通路,为癌症治疗中的耐药机制提供新见解。

3. **文献名称**: *TMEM141 as a novel biomarker in colorectal cancer: An immunohistochemical study*

**作者**: Lee S, et al. (2021)

**摘要**: 通过免疫组化分析TMEM141抗体标记的肿瘤组织样本,发现其在结直肠癌中高表达且与患者预后不良相关,提示其作为诊断标志物的潜力。

4. **文献名称**: *Functional characterization of TMEM141 in Alzheimer’s disease models*

**作者**: Johnson R, et al. (2022)

**摘要**: 研究利用TMEM141抗体探究其在阿尔茨海默病模型中的分布,发现其与β-淀粉样蛋白沉积区域共定位,可能通过影响神经元膜运输参与病理进程。

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**注意**:以上为模拟内容,实际文献需通过PubMed、Google Scholar等平台以“TMEM141 antibody”为关键词检索确认。若需具体文献,建议补充数据库访问权限或研究背景。

       

背景信息

The TMEM141 antibody is a research tool designed to target the transmembrane protein 141 (TMEM141), a poorly characterized protein encoded by the *TMEM141* gene in humans. TMEM141 is predicted to be a multi-pass transmembrane protein, suggesting roles in cellular membrane structures or transport processes. While its exact biological function remains unclear, studies link TMEM141 to cellular stress responses, mitochondrial regulation, and potential involvement in neurological or metabolic disorders.

TMEM141 antibodies are primarily used in basic research to investigate the protein’s expression, localization, and interactions. They enable detection via techniques like Western blotting, immunohistochemistry, and immunofluorescence. Some studies suggest TMEM141 may be upregulated in certain cancers or neurodegenerative conditions, making its antibody a potential biomarker-development candidate. However, limited commercial availability and a lack of extensive validation in diverse experimental models pose challenges.

Current research focuses on elucidating TMEM141’s molecular mechanisms, particularly its relationship to mitochondrial function and oxidative stress pathways. Species specificity (e.g., human, mouse) and antibody validation for specific applications remain critical considerations. As interest grows in understudied transmembrane proteins, TMEM141 antibodies may gain prominence in uncovering novel therapeutic targets or disease mechanisms. Further studies are needed to clarify its physiological and pathological relevance.

       
TMEM141抗体;TMEM141;TMEM141 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业,

成立日期 (2年)
注册资本 20万人民币
员工人数 1-10人
年营业额 ¥ 100万以内
经营模式 贸易,工厂,试剂,定制,服务
主营行业 抗体,蛋白组学,细胞生物学

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