GSTCD抗体—艾普蒂

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     Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: K562 cell lysate, Primary antibody: P10204(GSTCD Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 5 minutes    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P10204(GSTCD Antibody) at dilution 1/70. (Original magnification: ×200)    

  
  

The glutathione S-transferase C-terminal domain-containing (GSTCD) protein is encoded by the GSTCD gene, located on human chromosome 4q24. Initially identified through genome-wide association studies (GWAS), GSTCD has been linked to lung function parameters, particularly forced expiratory volume (FEV1) and the FEV1/forced vital capacity (FVC) ratio, suggesting a role in respiratory health. While its exact molecular function remains unclear, GSTCD is hypothesized to interact with glutathione S-transferases (GSTs), enzymes involved in detoxification and oxidative stress response. It may also influence ciliary function in airway epithelial cells, potentially impacting obstructive lung diseases like asthma and COPD.

GSTCD antibodies are tools developed to study the protein's expression, localization, and biological mechanisms. These antibodies enable detection of GSTCD in tissues (e.g., via Western blotting, immunohistochemistry) and facilitate research into its association with pulmonary pathophysiology. Studies using GSTCD antibodies have explored its tissue-specific expression patterns, particularly in the lung, and its potential regulatory roles in gene networks affecting airway function. Despite progress, further research is needed to clarify GSTCD's precise functional pathways and its contribution to disease susceptibility, highlighting the continued relevance of GSTCD antibodies in respiratory and molecular studies.