REG1B抗体—艾普蒂

The REG1B antibody targets the REG1B protein, a member of the regenerating islet-derived (REG) family, which plays roles in cell proliferation, regeneration, and inflammation. REG1B, also known as lithostathine-1β or pancreatic stone protein, is secreted primarily by pancreatic acinar cells and gastrointestinal tissues. It functions as a C-type lectin, potentially involved in calcium carbonate crystal inhibition, mucosal repair, and microbial defense. Dysregulation of REG1B is linked to pancreatic diseases (e.g., chronic pancreatitis, diabetes) and cancers (e.g., colorectal, gastric). The REG1B antibody is utilized in research to detect REG1B expression in tissues or biological fluids, aiding in understanding its pathological roles. It is critical for immunoassays (ELISA, immunohistochemistry) and functional studies exploring REG1B's interaction with receptors like EXTL3. Specificity and validation are essential due to homology with REG1A.