THNSL1抗体—艾普蒂

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     Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: K562 and 231 cell lysates, Primary antibody: P10058(THNSL1 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P10058(THNSL1 Antibody) at dilution 1/45. (Original magnification: ×200)    

  
  

THNSL1 (Threonine Synthase-Like 1) is a protein-coding gene implicated in cellular metabolic processes, particularly in amino acid biosynthesis. The THNSL1 enzyme shares structural homology with threonine synthase but lacks catalytic activity for threonine production, suggesting a regulatory or alternative functional role. It is expressed in various tissues, with higher levels observed in the brain, testes, and certain cancer cells. Studies link THNSL1 to cell proliferation and differentiation, potentially influencing tumorigenesis. For instance, elevated THNSL1 expression has been associated with poor prognosis in glioblastoma and colorectal cancer, possibly through interactions with metabolic pathways or signaling cascades like the PI3K/AKT axis.

THNSL1 antibodies are essential tools for investigating its biological function and clinical relevance. These antibodies enable detection and quantification of THNSL1 protein levels in cells or tissues via techniques such as Western blotting, immunohistochemistry, and immunofluorescence. Researchers utilize them to explore THNSL1's role in cancer progression, metabolic disorders, and neurological conditions. Commercial THNSL1 antibodies are typically validated for specificity against conserved epitopes, though variability in isoform recognition may require careful selection based on experimental needs. Ongoing research aims to clarify THNSL1's mechanistic contributions to disease, positioning it as a potential diagnostic marker or therapeutic target.