IFT27抗体—艾普蒂

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     The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P10033(IFT27 Antibody) at dilution 1/50. (Original magnification: ×200)    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using P10033(IFT27 Antibody) at dilution 1/50. (Original magnification: ×200)    

  
  

The interferon-induced transmembrane protein 27 (IFITM27) antibody is a tool used to study the IFITM protein family, which plays critical roles in innate immunity and cellular defense against viral infections. IFITM proteins, including IFITM1. IFITM2. and IFITM3. are induced by interferons and function to restrict viral entry by altering membrane fluidity or blocking viral fusion. While IFITM27 is less characterized compared to its well-studied counterparts, it is hypothesized to share functional similarities, such as involvement in antiviral responses or immune modulation.

IFITM27 antibodies are primarily utilized in research applications like Western blotting, immunofluorescence, and immunohistochemistry to detect protein expression, subcellular localization, and interactions in various cell types. These antibodies help elucidate IFITM27's role in viral pathogenesis (e.g., influenza, HIV, Zika) and its potential involvement in cancer progression, where IFITM proteins may influence metastasis or drug resistance.

Despite limited data on IFITM27 specifically, its antibody remains valuable for exploring tissue-specific expression patterns and regulatory mechanisms under interferon stimulation or pathogenic stress. Challenges include cross-reactivity with other IFITM family members, necessitating validation via knockout controls. Ongoing studies aim to clarify IFITM27's distinct functions and therapeutic potential in infectious and oncological diseases.