GOLGA7抗体—艾普蒂

The Golgin A7 (GOLGA7) antibody is a research tool used to detect and study the GOLGA7 protein, a member of the golgin family localized to the Golgi apparatus. GOLGA7 plays a critical role in maintaining Golgi structure and facilitating vesicle-mediated protein trafficking. It interacts with other golgins and small GTPases, such as ARF-like proteins, to regulate membrane tethering and cargo transport. GOLGA7 is also implicated in cellular processes like autophagy, cell adhesion, and signaling pathways. Dysregulation of GOLGA7 has been linked to cancers, neurodegenerative disorders, and ciliopathies, making it a target for disease mechanism studies. Antibodies against GOLGA7 (polyclonal or monoclonal) are widely used in techniques like Western blotting, immunofluorescence, and immunoprecipitation to analyze its expression, localization, and interactions. Recent studies highlight its potential role in viral infections, as some pathogens exploit Golgi components for replication. Validation of GOLGA7 antibodies includes testing in knockout cell lines to ensure specificity. Research continues to explore its functional diversity and therapeutic relevance in human diseases.