TSSK3抗体—艾普蒂

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     Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Huvec cell, Primary antibody: P04034(HOXC6 Antibody) at dilution 1/550, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute    

  
  

The TSSK3 (Testis-Specific Serine/Threonine Kinase 3) antibody is a research tool designed to detect and study the TSSK3 protein, a member of the testis-specific serine/threonine kinase family. TSSK3 is predominantly expressed in the testis, particularly during spermatogenesis, and plays a critical role in male germ cell development, including sperm maturation and function. It is characterized by a conserved kinase domain and unique N-terminal regions, which may regulate its substrate specificity and cellular localization.

TSSK3 antibodies are widely used in reproductive biology to investigate protein expression patterns, subcellular localization (e.g., in sperm tails or cytoplasm), and functional roles in fertility. These antibodies enable techniques like Western blotting, immunohistochemistry, and immunofluorescence to analyze TSSK3 in tissue samples, cell lines, or knockout models. Research has linked TSSK3 dysfunction to male infertility, making it a potential biomarker or therapeutic target. Additionally, studies explore its involvement in signaling pathways regulating sperm motility, capacitation, and acrosome reaction.

Commercial TSSK3 antibodies are typically validated for specificity and sensitivity, often generated using immunogenic peptide sequences from conserved regions. Their applications span basic research on spermatogenesis mechanisms and translational studies for contraceptive development or infertility diagnostics.