DCP1B抗体—艾普蒂

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     Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Ramos cell lysate, Primary antibody: P09592(DCP1B Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 1 minute    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P09592(DCP1B Antibody) at dilution 1/70. (Original magnification: ×200)    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using P09592(DCP1B Antibody) at dilution 1/70. (Original magnification: ×200)    

  
  

The DCP1B antibody is a tool used to detect and study the Decapping mRNA 1B (DCP1B) protein, a key component of the mRNA decapping complex involved in post-transcriptional gene regulation. DCP1B, along with DCP1A, facilitates mRNA degradation by removing the 5' cap structure, a critical step in controlling mRNA stability and turnover. This process is essential for regulating gene expression, particularly in response to cellular stress, developmental cues, or environmental changes.

DCP1B is implicated in diverse cellular functions, including cell cycle progression, apoptosis, and differentiation. Dysregulation of mRNA decapping has been linked to diseases such as cancer, neurodegenerative disorders, and viral infections. Researchers utilize DCP1B antibodies in techniques like Western blotting, immunofluorescence, and immunoprecipitation to investigate its expression, localization, and interactions within cellular pathways. These studies aim to uncover its role in maintaining mRNA homeostasis and its potential as a therapeutic target. Commercial DCP1B antibodies are typically validated for specificity and sensitivity, though performance may vary depending on epitope accessibility and experimental conditions. Ongoing research continues to explore DCP1B's regulatory mechanisms and its broader impact on cellular physiology and disease pathology.