DYNC1LI1抗体—艾普蒂

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     The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P09584(DYNC1LI1 Antibody) at dilution 1/25. (Original magnification: ×200)    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human brain tissue using P09584(DYNC1LI1 Antibody) at dilution 1/25. (Original magnification: ×200)    

  
  

The DYNC1LI1 antibody is a research tool designed to detect and study the cytoplasmic dynein 1 light intermediate chain 1 (DYNC1LI1), a critical subunit of the dynein motor protein complex. Dynein is a microtubule-associated motor protein involved in intracellular transport, organelle positioning, mitosis, and cell migration. DYNC1LI1. encoded by the *DYNC1LI1* gene, functions as part of the dynein-dynactin complex, facilitating cargo binding and regulating dynein’s motor activity.

Researchers use DYNC1LI1 antibodies in applications like Western blotting, immunofluorescence, and immunoprecipitation to investigate DYNC1LI1 expression, localization, and interactions. These studies are vital for understanding cellular processes such as neuronal transport, ciliary function, and cell division. Dysregulation of dynein complexes, including DYNC1LI1. has been linked to neurodevelopmental disorders, neurodegenerative diseases (e.g., ALS), and ciliopathies. The antibody’s specificity and reliability make it valuable for exploring dynein’s role in health and disease. Validated in various models (e.g., mammalian cells, tissues), DYNC1LI1 antibodies help uncover mechanisms underlying intracellular trafficking defects and potential therapeutic targets.