CNDP2抗体—艾普蒂

+ +

•  

   

     The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P09528(CNDP2 Antibody) at dilution 1/20. (Original magnification: ×200)    

  
  

•  

   

     The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P09528(CNDP2 Antibody) at dilution 1/20. (Original magnification: ×200)    

  
  

**Background of CNDP2 Antibody**

The CNDP2 (Carnosine Dipeptidase 2) gene encodes a cytosolic enzyme belonging to the M20 metalloprotease family, primarily involved in hydrolyzing dipeptides such as carnosine and homocarnosine. These dipeptides play roles in cellular antioxidant defense, pH buffering, and neurological modulation. CNDP2 is expressed in various tissues, including the liver, kidney, and brain, and its activity is linked to metabolic and neurodegenerative pathways.

CNDP2 antibodies are immunological tools designed to detect and study the expression, localization, and function of the CNDP2 protein. Research has highlighted its potential relevance in diseases like diabetes, cancer, and Alzheimer’s, where altered carnosine metabolism or oxidative stress may contribute to pathology. For instance, CNDP2 polymorphisms are associated with diabetic nephropathy risk, while its dysregulation in tumors suggests a role in cancer cell survival.

These antibodies are widely used in techniques like Western blotting, immunohistochemistry, and ELISA to explore CNDP2’s biological mechanisms or validate its involvement in disease models. Their development and specificity are critical for advancing studies on metabolic regulation, neurodegeneration, and therapeutic targeting.