CAMKK1抗体—艾普蒂

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     Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: 293T cell lysate, Primary antibody: P09430(CAMKK1 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P09430(CAMKK1 Antibody) at dilution 1/35. (Original magnification: ×200)    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P09430(CAMKK1 Antibody) at dilution 1/35. (Original magnification: ×200)    

  
  

The calcium/calmodulin-dependent protein kinase kinase 1 (CAMKK1) antibody is a key tool for studying the CAMKK1 enzyme, a serine/threonine kinase within the Ca²⁺/calmodulin-dependent protein kinase (CAMK) family. CAMKK1 acts as an upstream regulator of AMP-activated protein kinase (AMPK) and other CAMK members, playing pivotal roles in cellular energy homeostasis, cell growth, autophagy, and stress responses. It is implicated in diverse physiological and pathological processes, including cancer progression, metabolic disorders, and neurodegenerative diseases.

CAMKK1 antibodies are designed to detect and quantify CAMKK1 expression in various biological samples. These antibodies are typically developed using immunogens derived from specific regions of the human CAMKK1 protein and are validated for applications such as Western blotting, immunohistochemistry (IHC), immunofluorescence (IF), and flow cytometry. Researchers rely on these antibodies to investigate CAMKK1's tissue distribution, subcellular localization, and interaction with downstream targets.

High-quality CAMKK1 antibodies exhibit specificity, sensitivity, and minimal cross-reactivity with homologous proteins like CAMKK2. Their utility extends to both basic research and preclinical studies, particularly in exploring CAMKK1's role as a potential therapeutic target. Proper validation using knockout controls or peptide blocking experiments is essential to ensure antibody reliability. Commercial variants may differ in host species (e.g., rabbit, mouse), clonality (monoclonal/polyoclonal), and conjugation tags, allowing flexibility for experimental design.