ZNF8抗体—艾普蒂

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     Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: SKOV3, A549 and HEPG2 cell lysates, Primary antibody: P09249(ZNF8 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P09249(ZNF8 Antibody) at dilution 1/30. (Original magnification: ×200)    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P09249(ZNF8 Antibody) at dilution 1/30. (Original magnification: ×200)    

  
  

**Background of ZNF8 Antibody**

Zinc finger protein 8 (ZNF8), a member of the zinc finger protein family, is characterized by conserved C2H2-type zinc finger domains that mediate sequence-specific DNA binding. These proteins play critical roles in transcriptional regulation, chromatin remodeling, and cellular processes such as differentiation and apoptosis. ZNF8. though less studied compared to other zinc finger proteins, is implicated in modulating gene expression networks, potentially influencing cell cycle control and stress responses.

Antibodies targeting ZNF8 are essential tools for investigating its expression, localization, and function in biological systems. They enable detection and quantification of ZNF8 in techniques like Western blotting, immunohistochemistry, and immunofluorescence. Research suggests ZNF8 may interact with other regulatory proteins or nucleic acids, though its precise mechanisms remain under exploration.

Interest in ZNF8 has grown due to its potential links to diseases. For example, aberrant expression of zinc finger proteins is often associated with cancers or neurological disorders. Studies using ZNF8 antibodies aim to clarify its role in pathological contexts, such as tumor progression or developmental abnormalities. Additionally, ZNF8 antibodies contribute to epigenetic studies, as zinc finger proteins frequently participate in chromatin modification complexes.

Further characterization of ZNF8 and its antibody-based detection could advance understanding of its physiological significance and therapeutic potential in human diseases.