ZNF449抗体—艾普蒂

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     The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P09244(ZNF449 Antibody) at dilution 1/50. (Original magnification: ×200)    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using P09244(ZNF449 Antibody) at dilution 1/50. (Original magnification: ×200)    

  
  

The ZNF449 antibody is a research tool designed to detect and study the zinc finger protein 449 (ZNF449), a member of the zinc finger protein family characterized by conserved C2H2-type zinc finger motifs. These proteins are implicated in DNA binding, transcriptional regulation, and chromatin remodeling. ZNF449 is thought to function as a transcription factor, potentially modulating gene expression in cellular processes such as differentiation, proliferation, or apoptosis, though its precise biological roles remain under investigation.

As a reagent, the ZNF449 antibody is commonly used in techniques like Western blotting, immunofluorescence, and immunohistochemistry to identify the protein's expression patterns, localization, and abundance in various tissues or cell types. Its development is critical for exploring ZNF449's involvement in diseases, including cancer or genetic disorders, where dysregulation of zinc finger proteins is often observed. Researchers rely on validated ZNF449 antibodies to ensure specificity and sensitivity, minimizing cross-reactivity with homologous proteins.

Current studies utilizing this antibody aim to clarify ZNF449's interactions with DNA or other regulatory proteins, its role in signaling pathways, and its potential as a biomarker or therapeutic target. However, comprehensive functional insights require further experimental validation, emphasizing the antibody's importance in advancing molecular and cellular biology research.