ZNF266抗体—艾普蒂

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     The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P09234(ZNF266 Antibody) at dilution 1/30. (Original magnification: ×200)    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P09234(ZNF266 Antibody) at dilution 1/30. (Original magnification: ×200)    

  
  

ZNF266 antibody is a research tool designed to detect and study the zinc finger protein 266 (ZNF266), a member of the Krüppel-associated box (KRAB) domain-containing zinc finger protein (KZNF) family. ZNF266 is encoded by the *ZNF266* gene in humans and is characterized by multiple C2H2-type zinc finger motifs, which enable sequence-specific DNA or RNA binding. As a transcriptional regulator, ZNF266 is implicated in epigenetic silencing, chromatin remodeling, and gene expression modulation, particularly in developmental processes and cellular differentiation. Dysregulation of ZNF266 has been loosely associated with cancers, neurological disorders, and immune-related conditions, though its precise biological roles remain under investigation.

The ZNF266 antibody is typically developed using recombinant protein fragments or synthetic peptides as immunogens, yielding polyclonal or monoclonal variants. It is widely utilized in techniques like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to analyze ZNF266 expression patterns, subcellular localization, and interactions in various tissues or cell lines. Researchers employ this antibody to explore ZNF266's involvement in disease mechanisms, such as tumor suppression or oncogenesis, and its potential as a biomarker. However, specificity and validation data (e.g., knockout controls) are critical due to homology among zinc finger proteins. Commercial availability through biotechnology vendors supports its use in both basic and translational research contexts.