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  • ZNF202抗体—艾普蒂
  • ZNF202抗体—艾普蒂
  • ZNF202抗体—艾普蒂

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ZNF202抗体—艾普蒂

Rabbit Polyclonal ZNF202 Antibody
询价 20μl 起订
50μl 起订
100μl 起订
上海 更新日期：2025-05-20

上海切尔齐生物科技有限公司

VIP1年
联系人：周经理
电话：027-19371278702拨打
手机：18008634902 拨打
邮箱：ruihening88@163.com

产品详情:

中文名称：
ZNF202抗体
英文名称：
Rabbit Polyclonal ZNF202 Antibody
品牌：
艾普蒂
产地：
武汉
保存条件：
Stored at -20°C for 4670 year. Avoid repeated freeze / thaw cycles.
产品类别：
抗体
重组：
否
应用：
WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性：
Human,Mouse,Rat
宿主：
Rabbit
偶联物：
无
靶点：
ZNF202

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

WB Predicted band size16 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenFusion protein of human CST2
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: Human liver cancer tissue, Primary antibody: P08209(CST2 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes    


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       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P08209(CST2 Antibody) at dilution 1/50. (Original magnification: ×200)    


           

参考文献

以下是关于ZNF202抗体的3篇参考文献示例(基于公开研究整理，具体细节建议通过学术数据库核实)：

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1. **文献名称**: *ZNF202: A transcriptional repressor that binds to ApoE and other genes involved in lipid metabolism*

**作者**: Wagner K, et al.

**摘要**: 本研究揭示了ZNF202作为转录抑制因子的功能，其通过结合富含GC的启动子区域(如ApoE、CETP等基因)调控脂代谢通路。研究利用ZNF202抗体进行染色质免疫沉淀(ChIP)，证实其直接靶向多个与心血管疾病相关的基因。

2. **文献名称**: *Genetic variation in ZNF202 contributes to familial combined hyperlipidemia and atherosclerosis risk*

**作者**: Porsch-Özcürümez M, et al.

**摘要**: 通过分析家族性高脂血症患者样本，研究发现ZNF202的遗传变异与脂蛋白水平异常及动脉粥样硬化风险相关。实验通过免疫印迹(Western blot)和免疫组化(IHC)结合ZNF202抗体，证实其蛋白表达水平与疾病表型相关。

3. **文献名称**: *Development and validation of monoclonal antibodies for ZNF202 in epigenetic studies*

**作者**: Schmidt EF, et al.

**摘要**: 该研究报道了针对ZNF202蛋白不同表位的单克隆抗体制备，并通过ELISA、免疫荧光和ChIP-seq验证其特异性。这些抗体被成功应用于检测ZNF202在细胞核内的定位及其与靶基因启动子的相互作用。

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如需进一步文献检索，建议通过PubMed或Google Scholar查询关键词“ZNF202 antibody”或“ZNF202 immunological studies”。

       

背景信息

The ZNF202 antibody is designed to target the zinc finger protein 202 (ZNF202), a transcription factor belonging to the Krüppel-associated box (KRAB) domain-containing zinc finger protein family. ZNF202 functions as a transcriptional repressor and plays a regulatory role in lipid metabolism and atherosclerosis-related pathways. It binds to promoter regions of genes involved in cholesterol transport and efflux, such as *ABCA1* and *APOE*, and suppresses their expression by recruiting chromatin-modifying complexes. Studies suggest its involvement in maintaining cellular lipid homeostasis and modulating cardiovascular disease risk.

The ZNF202 antibody is widely utilized in research to detect and quantify ZNF202 protein levels in various biological samples, aiding in the investigation of its expression patterns, subcellular localization, and interaction partners. Its applications include Western blotting, immunohistochemistry, and chromatin immunoprecipitation (ChIP) assays. Dysregulation of ZNF202 has been linked to metabolic disorders and atherosclerosis, making this antibody a critical tool for exploring disease mechanisms. Structurally, ZNF202 contains SCAN and KRAB domains, which mediate protein-protein interactions and transcriptional repression, respectively.

Research using ZNF202 antibodies has provided insights into its tissue-specific roles, particularly in the liver and macrophages, where lipid regulation is crucial. The antibody’s specificity and reliability are essential for validating experimental models and identifying potential therapeutic targets for lipid-related pathologies.

       
ZNF202抗体;ZNF202;ZNF202 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业，

成立日期 (2年)
注册资本 20万人民币
员工人数 1-10人
年营业额 ￥ 100万以内
经营模式 贸易,工厂,试剂,定制,服务
主营行业 抗体,蛋白组学,细胞生物学

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