ZNF672抗体—艾普蒂

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     The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using P09170(ZNF672 Antibody) at dilution 1/25. (Original magnification: ×200)    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P09170(ZNF672 Antibody) at dilution 1/25. (Original magnification: ×200)    

  
  

The ZNF672 antibody is a specialized tool used to detect and study the Zinc Finger Protein 672 (ZNF672), a member of the zinc finger protein family. Zinc finger proteins are characterized by finger-like structural domains that bind to DNA or RNA, playing critical roles in transcriptional regulation, chromatin remodeling, and cellular differentiation. ZNF672. encoded by the *ZNF672* gene on human chromosome 1q25.3. is hypothesized to function as a transcriptional regulator, though its precise biological mechanisms remain under investigation. Studies suggest its involvement in gene silencing, cell cycle control, and potential roles in neurodevelopment or cancer progression, as aberrant expression has been observed in certain tumors and neurological disorders.

ZNF672 antibodies are typically polyclonal or monoclonal antibodies generated by immunizing hosts (e.g., rabbits or mice) with synthetic peptides or recombinant protein fragments corresponding to specific epitopes of ZNF672. These antibodies enable researchers to identify ZNF672 in techniques like Western blotting, immunohistochemistry (IHC), immunofluorescence (IF), and chromatin immunoprecipitation (ChIP). Validation parameters, including specificity (via knockout controls), cross-reactivity, and optimal dilution ratios, are critical to ensure reliable results.

Research utilizing ZNF672 antibodies has contributed to understanding its expression patterns across tissues, subcellular localization (primarily nuclear), and interactions with other regulatory proteins. Such studies aim to unravel its role in disease pathways or developmental processes, highlighting its potential as a biomarker or therapeutic target. Commercial availability of ZNF672 antibodies from multiple suppliers has facilitated its integration into diverse experimental workflows in molecular biology and clinical research.