反式玉米素 1637-39-4

反式玉米素是一类嘌呤类的植物细胞分裂素，最初是从幼嫩的玉米芯中发现分离出来的，是植物内源性的一种植物生长调节剂，功能上不仅促进侧芽生长，刺激细胞分化（侧端优势)，促进愈伤组织和种子发芽，还能防止叶片衰老，逆转芽部受到的毒素伤害和抑制过度根部形成。高浓度的玉米素还能产生不定芽分化。另外，大量证据证明玉米素具有许多生物学效应，比如在人体系统有抗细胞凋亡，抗氧化，保持年轻化和抗衰老功能。

rans-Zeatin is a cytokinin plant growth regulator with antioxidant and neuroprotective activities.^1,2,3,4 It binds to the cytokinin receptor Arabidopsis histidine kinase 3 (AHK3) with a K_D value of 1.3 nM.³ trans-Zeatin increases chlorophyll levels in etiolated Cucumus sativus cotyledons in a concentration-dependent manner.¹ It increases callus growth and shoot formation in N. tabacum calluses when used at concentrations of 5 and 50 µM.² trans-Zeatin (25-100 µM) reduces production of reactive oxygen species (ROS) induced by amyloid β (25-35) (Aβ25-35) in PC12 cells.⁴ It reduces scopolamine-induced spontaneous alternations in the Y-maze, indicating enhanced spatial memory, in mice when administered at doses of 1.5, 3, and 4.5 mg/kg per day.

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