TSHR抗体促甲状腺激素受体抗体

TSHR抗体

其它名称：促甲状腺激素受体抗体，TSHR抗体,TSHR antibody，TRAb

货号：TR1011

应用：CLIA

特异性：Human TSHR

来源：Mouse

存贮：-20℃

TSHR促甲状腺激素受体是一种接受促甲状腺激素信号，刺激细胞生成甲状腺激素和三碘甲状腺激素的跨膜受体。促甲状腺激素受体是膜内在蛋白中G蛋白偶联受体超家族的一员，与Gs蛋白相连接。促甲状腺激素受体抗体又称膜受体抗体，是直接作用于甲状腺细胞膜上的TSH受体的抗体，属免疫球蛋白IgG。促甲状腺素受体(抗体)是一类可以特异性结合促甲状腺素受体的多克隆抗体，主要用于检测促甲状腺素受体蛋白的免疫学实验。

Thyroid stimulating hormone receptor (TSHR) is a guanine nucleotide-binding protein-coupled seven-transmembrane-domain receptor that controls the differentiation, growth, and function of the thyroid gland through stimulation of adenylyl cyclase and phospholipase C pathways. Thyroid stimulating hormone (TSH) is the main TSHR ligand, and unliganded receptor remains silent due to the interaction of its large extracellular domain with the extracellular loops of the serpentine. The TSHR gene is highly mutagenic and constitutively active mutations have been extensively described.

注意事项 ：

1.本品为蛋白质制剂，未添加任何防腐剂和保护剂，在 2-8 ℃可以短暂保存。

2.本品仅作为诊断试剂原辅材料，不得用于诊断或治疗。