甲状腺过氧化物酶TPO多抗

TPO多抗

其它名称：甲状腺过氧化物酶TPO多抗,TPO polyclonal antibody，TPO多克隆抗体

货号：grTP1-01A

应用：CLIA，POCT

特异性：Human TPO

来源：Goat

存贮：-20℃

产品说明

甲状腺过氧化物酶（thyroid　peroxidase，TPO）是甲状腺素合成所必需的一种酶，针对它产生的自身抗体为抗甲状腺过氧化物酶抗体（TPOAb），正常情况下TPO不进入血液，在甲状腺发生病变、甲状腺滤泡细胞被破坏后溢出血液刺激机体产生TPOAb。

This product is for research use only. It is not intended for diagnostic or therapeutic use.

注意事项：

1. 本品为蛋白质制剂，未添加任何防腐剂和保护剂，在2-8 ℃可以短暂保存。

2.本品仅作为诊断试剂原辅材料，不得用于诊断或治疗。

Thyroid peroxidase is an ∼105 kDa heme-containing glycoprotein that belongs to a family of mammalian peroxidases that includes myeloperoxidase, lactoperoxidase, eosinophil peroxidase, and salivary peroxidase. TPO is located on the apical membrane of thyrocytes where it catalyzes iodination of TG and coupling of iodotyrosines to form iodothyronines attached to TG. However, in vitro studies have shown that such functions are not unique to TPO in that lactoperoxidase and myeloperoxidase can also serve as catalysts for both iodination and coupling.