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  • CARD17抗体;CARD17 Antibody—艾普蒂
  • CARD17抗体;CARD17 Antibody—艾普蒂
  • CARD17抗体;CARD17 Antibody—艾普蒂

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CARD17抗体;CARD17 Antibody—艾普蒂

Rabbit Polyclonal CARD17 Antibody
询价 20μl 起订
50μl 起订
100μl 起订
上海 更新日期:2025-05-26

上海切尔齐生物科技有限公司

VIP1年
联系人:周经理
电话:027-19371278702拨打
手机:18008634902 拨打
邮箱:nuodina88@163.com

产品详情:

中文名称:
CARD17抗体
英文名称:
Rabbit Polyclonal CARD17 Antibody
品牌:
艾普蒂
产地:
武汉
保存条件:
Stored at -20°C for 6175 year. Avoid repeated freeze / thaw cycles.
产品类别:
抗体
重组:
应用:
WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性:
Human,Mouse,Rat
宿主:
Rabbit
偶联物:
靶点:
CARD17

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/1000-1/5000 Human,Mouse,Rat
   

产品详情

AliasesINCA
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenSynthetic peptide of human CARD17
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P11623(CARD17 Antibody) at dilution 1/50. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P11623(CARD17 Antibody) at dilution 1/50. (Original magnification: ×200)    


           

参考文献

以下是假设性的参考文献示例(实际文献需通过学术数据库验证):

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1. **"CARD17 negatively regulates NF-κB signaling by inhibiting ubiquitination of NEMO"**

*作者:Smith J, et al. (2020)*

**摘要**:本研究揭示CARD17通过干扰NEMO的泛素化抑制NF-κB通路,Western blot中使用特异性CARD17抗体验证其蛋白表达水平。

2. **"Characterization of a novel polyclonal antibody against human CARD17 for apoptosis assays"**

*作者:Zhang L, et al. (2021)*

**摘要**:开发并验证了一种兔源CARD17多克隆抗体,适用于免疫组化及流式细胞术,证实其在胃癌细胞凋亡中的调控作用。

3. **"CARD17 modulates caspase-1 activation in inflammasome pathways"**

*作者:Lee S, et al. (2019)*

**摘要**:通过免疫共沉淀(使用CARD17抗体)发现CARD17与caspase-1相互作用,调控炎症小体活性,影响IL-1β成熟。

4. **"The CARD family proteins in inflammatory diseases: Focus on CARD17"**

*作者:Brown K, et al. (2018)*

**摘要**:综述CARD蛋白在炎症中的功能,提及CARD17抗体在研究其组织分布及疾病模型中的应用。

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**注意**:以上为示例,实际文献需通过PubMed/Google Scholar检索确认。建议使用关键词“CARD17 antibody”或“CARD17 function”查找最新研究。

       

背景信息

The CARD17 antibody targets the Caspase Recruitment Domain (CARD)-containing protein 17. a member of the CARD protein family involved in apoptosis, inflammation, and immune regulation. CARD proteins typically function as adaptors in signaling pathways, mediating interactions between caspases, kinases, or other regulatory molecules. CARD17. though less characterized than other CARD family members (e.g., CARD11. CARD14), is proposed to modulate NF-κB and caspase-dependent pathways, potentially acting as an inhibitor or activator depending on cellular context. Its expression has been linked to immune cells and certain cancers, suggesting roles in tumorigenesis or immune response modulation. Antibodies against CARD17 are primarily used in research to detect protein expression, study its interactions, and elucidate its biological functions. Commercial CARD17 antibodies are often validated for applications like Western blotting, immunohistochemistry, or immunofluorescence. However, its precise physiological and pathological roles remain under investigation, partly due to limited studies and potential functional redundancy within the CARD family. Developing specific, high-affinity CARD17 antibodies remains critical for clarifying its role in cellular signaling and disease mechanisms.
       
CARD17抗体;CARD17;CARD17 Antibody;

公司简介

生物技术有限公司

成立日期 (2年)
注册资本 20万人民币
员工人数 1-10人
年营业额 ¥ 100万以内
经营模式 贸易,工厂,试剂,定制,服务
主营行业 抗体,植物生物技术,细胞培养,蛋白组学

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