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  • MTARC1抗体;MTARC1 Antibody—艾普蒂
  • MTARC1抗体;MTARC1 Antibody—艾普蒂
  • MTARC1抗体;MTARC1 Antibody—艾普蒂

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MTARC1抗体;MTARC1 Antibody—艾普蒂

Rabbit Polyclonal MTARC1 Antibody
询价 20μl 起订
50μl 起订
100μl 起订
上海 更新日期：2025-05-26

上海切尔齐生物科技有限公司

VIP1年
联系人：周经理
电话：027-19371278702拨打
手机：18008634902 拨打
邮箱：nuodina88@163.com

产品详情:

中文名称：
MTARC1抗体
英文名称：
Rabbit Polyclonal MTARC1 Antibody
品牌：
艾普蒂
产地：
武汉
保存条件：
Stored at -20°C for 6115 year. Avoid repeated freeze / thaw cycles.
产品类别：
抗体
重组：
否
应用：
WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性：
Human,Mouse,Rat
宿主：
Rabbit
偶联物：
无
靶点：
MTARC1

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

产品详情

AliasesMARC1; MOSC1
WB Predicted band size37 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenSynthetic peptide of human MTARC1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: HepG2 cells, Primary antibody: P11528(MTARC1 Antibody) at dilution 1/1400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using P11528(MTARC1 Antibody) at dilution 1/40. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P11528(MTARC1 Antibody) at dilution 1/40. (Original magnification: ×200)    


           

参考文献

以下是3条关于MTARC1抗体的参考文献概览(注：文献为虚拟示例，实际研究需以真实数据库检索结果为准)：

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1. **文献名称**: "Characterization of MTARC1 as a mitochondrial enzyme involved in drug metabolism"

**作者**: Grünebaum et al. (2018)

**摘要**: 研究利用MTARC1特异性抗体，通过免疫印迹和免疫荧光技术验证其在肝细胞线粒体中的定位，并发现其参与药物前体(如抗病毒药物)的活化过程。

2. **文献名称**: "The role of mARC1 in lipid homeostasis and non-alcoholic fatty liver disease"

**作者**: Havemeyer et al. (2011)

**摘要**: 通过MTARC1抗体检测发现，mARC1在小鼠肝脏中高表达，敲除该基因会导致脂质代谢异常，提示其与脂肪肝疾病的潜在关联。

3. **文献名称**: "Development of a monoclonal antibody for human MTARC1 and its diagnostic applications"

**作者**: Kurian et al. (2020)

**摘要**: 报道一种新型MTARC1单克隆抗体的开发，验证其在ELISA和免疫组化中的特异性，并探索其在肝病生物标志物检测中的应用潜力。

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**提示**：实际研究中建议通过PubMed或Google Scholar以关键词“MTARC1 antibody”或“mARC1 antibody”检索最新文献，并注意区分基因别名(如MTARC1可能标注为“mARC1”或“MOSC1”)。

       

背景信息

The mitochondrial amidoxime reducing component 1 (MTARC1), also known as MOSC2. is a molybdenum-containing enzyme encoded by the *MTARC1* gene. It belongs to the mARC enzyme family, which catalyzes the reduction of N-hydroxylated compounds, playing a role in detoxifying xenobiotics and endogenous metabolites. MTARC1 is anchored to the mitochondrial outer membrane and contains a molybdenum cofactor (MoCo)-binding domain critical for its enzymatic activity.

Research on MTARC1 has gained attention due to its involvement in lipid metabolism and association with metabolic disorders. Studies link MTARC1 dysfunction to non-alcoholic fatty liver disease (NAFLD), insulin resistance, and cardiovascular diseases. Its role in modulating hepatic steatosis and triglyceride levels highlights its potential as a therapeutic target.

MTARC1 antibodies are essential tools for detecting protein expression, localization, and post-translational modifications. They are widely used in techniques like Western blotting, immunohistochemistry, and immunofluorescence to study MTARC1 in cell lines, animal models, and human tissues. Commercially available antibodies are typically validated for specificity using knockout controls. Recent studies also employ MTARC1 antibodies to explore its interaction partners and regulatory mechanisms in mitochondrial pathways.

Overall, MTARC1 antibodies facilitate mechanistic insights into its biological functions and disease relevance, bridging gaps between genetic associations and metabolic pathophysiology.

       
MTARC1抗体;MTARC1;MTARC1 Antibody;

公司简介

生物技术有限公司

成立日期 (2年)
注册资本 20万人民币
员工人数 1-10人
年营业额 ￥ 100万以内
经营模式 贸易,工厂,试剂,定制,服务
主营行业 抗体,植物生物技术,细胞培养,蛋白组学

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