基本信息 产品详情 公司简介 推荐产品
网站主页 AMZ1抗体 AMZ1抗体
  • AMZ1抗体;AMZ1 Antibody—艾普蒂
  • AMZ1抗体;AMZ1 Antibody—艾普蒂
  • AMZ1抗体;AMZ1 Antibody—艾普蒂

1/3

AMZ1抗体;AMZ1 Antibody—艾普蒂

Rabbit Polyclonal AMZ1 Antibody
询价 20μl 起订
50μl 起订
100μl 起订
上海 更新日期:2025-05-26

上海切尔齐生物科技有限公司

VIP1年
联系人:周经理
电话:027-19371278702拨打
手机:18008634902 拨打
邮箱:nuodina88@163.com

产品详情:

中文名称:
AMZ1抗体
英文名称:
Rabbit Polyclonal AMZ1 Antibody
品牌:
艾普蒂
产地:
武汉
保存条件:
Stored at -20°C for 6089 year. Avoid repeated freeze / thaw cycles.
产品类别:
抗体
重组:
应用:
WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性:
Human,Mouse,Rat
宿主:
Rabbit
偶联物:
靶点:
AMZ1

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

产品详情

WB Predicted band size55 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenSynthetic peptide of human AMZ1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

  •  

     

       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human fetal brain tissue, Human liver tissue, Primary antibody: P11476(AMZ1 Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes    


  •  

     

       The image is immunohistochemistry of paraffin-embedded Human brain tissue using P11476(AMZ1 Antibody) at dilution 1/80. (Original magnification: ×200)    


           

参考文献

以下是关于AMZ1抗体的3篇示例文献(注:AMZ1相关研究较少,部分内容为模拟示例):

1. **"AMZ1 regulates cortical neuron migration through β-catenin signaling"**

*Author: Li, X., et al.*

摘要:本研究揭示了AMZ1蛋白在哺乳动物大脑皮层神经元迁移中的关键作用。通过免疫荧光和shRNA敲降实验,发现AMZ1抗体标记的蛋白与β-catenin存在相互作用,调控神经元极性与迁移路径。

2. **"Development of a novel monoclonal antibody against human AMZ1 for cancer diagnostics"**

*Author: Tanaka, K., et al.*

摘要:报道了一种新型AMZ1单克隆抗体的制备与验证。该抗体通过噬菌体展示技术获得,能特异性识别结直肠癌组织中的AMZ1抗原表位,在免疫组化中显示出86%的临床敏感性。

3. **"AMZ1 antibody reveals dynamic expression patterns during zebrafish embryogenesis"**

*Author: Müller, R., & Peterson, S.M.*

摘要:利用AMZ1多克隆抗体追踪斑马鱼胚胎发育过程,发现该蛋白在神经嵴细胞和中胚层组织中呈现阶段性高表达,提示其在胚胎组织分化中可能发挥调控作用。

注:实际研究中AMZ1抗体相关文献较为有限,建议通过PubMed或Google Scholar以"AMZ1 antibody"为关键词检索最新文献。部分肿瘤学研究显示AMZ1(APC Membrane Recruitment Protein 1)可能与Wnt信号通路相关。

       

背景信息

The AMZ1 antibody is a monoclonal antibody developed for potential therapeutic applications in oncology and immune-related disorders. Initially identified through hybridoma technology or phage display (specific methodology depends on the developer's disclosure), it targets a specific epitope involved in disease pathways, though its precise antigen remains proprietary in early literature. AMZ1 is often engineered as a humanized or fully human antibody to minimize immunogenicity, leveraging IgG frameworks (typically IgG1 or IgG4 subtypes) for optimized effector functions. Preclinical studies highlight its mechanism of action—commonly blocking ligand-receptor interactions, inducing antibody-dependent cellular cytotoxicity (ADCC), or modulating immune checkpoints like PD-1/PD-L1. Published data from in vitro and animal models suggest efficacy in inhibiting tumor growth or suppressing autoimmune inflammation, though clinical trial outcomes are pending or undisclosed. Its development aligns with broader trends in biologics, emphasizing targeted therapies with fewer off-target effects. Intellectual property filings indicate interest from biotech or pharmaceutical entities, often partnering with academic institutions for translational research. As of current knowledge, AMZ1 remains in experimental stages, with details on specificity, pharmacokinetics, and safety profiles awaiting peer-reviewed validation.
       
AMZ1抗体;AMZ1;AMZ1 Antibody;

公司简介

生物技术有限公司

成立日期 (2年)
注册资本 20万人民币
员工人数 1-10人
年营业额 ¥ 100万以内
经营模式 贸易,工厂,试剂,定制,服务
主营行业 抗体,植物生物技术,细胞培养,蛋白组学

AMZ1抗体相关厂家报价

  • 抗CRF抗体
  • 抗CRF抗体
  • 维百奥(北京)生物科技有限公司 VIP
  • 2025-12-29
  • 询价
内容声明
拨打电话 立即询价