FDXR抗体;FDXR Antibody—艾普蒂

The FDXR (ferredoxin reductase) antibody is a crucial tool in studying the role of the FDXR protein, a mitochondrial enzyme involved in electron transfer reactions. FDXR catalyzes the transfer of electrons from NADPH to ferredoxin, a process essential for steroidogenesis, heme biosynthesis, and iron-sulfur (Fe-S) cluster assembly. It is integral to mitochondrial function, particularly in cytochrome P450 systems. Dysregulation of FDXR has been linked to oxidative stress, mitochondrial disorders, and pathologies like neurodegenerative diseases and cancer. Researchers use FDXR antibodies in techniques such as Western blotting, immunohistochemistry, and immunofluorescence to assess protein expression, localization, and mitochondrial health. These antibodies help elucidate FDXR's role in cellular stress responses, DNA damage repair, and apoptosis. Recent studies also explore FDXR as a potential biomarker for radiation exposure due to its sensitivity to ionizing radiation. Validated antibodies with high specificity are critical for ensuring experimental reproducibility in both basic research and clinical investigations.