MANSC1抗体;MANSC1 Antibody—艾普蒂

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     The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P10158(MANSC1 Antibody) at dilution 1/105. (Original magnification: ×200)    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P10158(MANSC1 Antibody) at dilution 1/105. (Original magnification: ×200)    

  
  

The MANSC1 (MANSC domain-containing protein 1) antibody targets a protein encoded by the *MANSC1* gene, which belongs to the Manscin family. MANSC1 is a conserved, yet understudied protein containing a characteristic MANSC domain, implicated in cell adhesion, differentiation, and extracellular matrix interactions. While its precise molecular function remains unclear, studies suggest its potential role in regulating cellular processes linked to tumorigenesis, immune responses, and tissue development. Dysregulation of MANSC1 has been observed in cancers, including hepatocellular carcinoma and breast cancer, where it may influence metastasis or chemoresistance.

The MANSC1 antibody is primarily utilized in research to detect and quantify endogenous MANSC1 protein expression via techniques like Western blotting, immunohistochemistry, and immunofluorescence. It serves as a critical tool for exploring MANSC1's localization, interaction partners, and biological significance. Commercial MANSC1 antibodies are typically raised in rabbits or mice, with validation in specific cell lines or tissues. Researchers often verify specificity using knockout controls or siRNA-mediated silencing. Despite limited clinical applications to date, ongoing studies aim to clarify its role as a biomarker or therapeutic target, driving demand for reliable antibodies in mechanistic and translational investigations.