GH2抗体;GH2 Antibody—艾普蒂

+ +

•  

   

     Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Human placenta tissue, Primary antibody: P08366(GH2 Antibody) at dilution 1/700, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds    

  
  

•  

   

     The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P08366(GH2 Antibody) at dilution 1/60. (Original magnification: ×200)    

  
  

•  

   

     The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P08366(GH2 Antibody) at dilution 1/60. (Original magnification: ×200)    

  
  

GH2 antibody targets growth hormone 2 (GH2), a peptide hormone primarily involved in growth regulation, metabolism, and cell repair. GH2. encoded by the *GH2* gene, is structurally similar to growth hormone 1 (GH1) but differs in expression patterns and evolutionary conservation. While GH1 is the dominant form in humans, GH2 is more prominent in certain species, such as fish, and may play roles in developmental or species-specific physiological processes.

In research, GH2 antibodies are critical tools for detecting and quantifying GH2 in biological samples via techniques like ELISA, Western blotting, or immunohistochemistry. These antibodies help elucidate GH2's functional roles, including its interaction with growth hormone receptors (GHR) and involvement in signaling pathways like JAK-STAT. Dysregulation of GH2-related pathways has been linked to growth disorders, metabolic syndromes, and some cancers, making such antibodies valuable for both basic and clinical studies.

Most GH2 antibodies are monoclonal or polyclonal, raised in hosts like rabbits or mice, with specificity validated through epitope mapping. Cross-reactivity with GH1 or other pituitary hormones is a key consideration during experimental design. Ongoing research focuses on refining antibody specificity and exploring therapeutic applications, such as targeting GH2 in hormone-responsive diseases.