NUDT6抗体—艾普蒂

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     Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Rat heart tissue, Primary antibody: P09116(NUDT6 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 seconds    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P09116(NUDT6 Antibody) at dilution 1/25. (Original magnification: ×200)    

  
  

The NUDT6 (Nudix Hydrolase 6) antibody is a tool used to study the NUDT6 protein, a member of the Nudix hydrolase family involved in nucleotide metabolism and RNA processing. NUDT6. encoded by the *NUDT6* gene, is linked to regulating fibroblast growth factor 2 (FGF2) through its antisense RNA transcript, influencing cell proliferation, differentiation, and apoptosis. The antibody targets specific epitopes of the NUDT6 protein, enabling its detection in techniques like Western blotting, immunohistochemistry (IHC), immunofluorescence (IF), and flow cytometry.

Research using NUDT6 antibodies has elucidated its role in cancers, including gliomas and breast cancer, where altered expression correlates with tumor progression. It also aids in studying neurodegenerative diseases, as NUDT6 may impact neuronal survival. Validated for specificity in human samples, the antibody (often rabbit or mouse-derived) helps identify NUDT6's subcellular localization, typically in the nucleus or cytoplasm, depending on cell type.

Recent studies highlight its potential as a biomarker or therapeutic target, emphasizing its regulatory interplay with growth factors and stress responses. Users should optimize antibody protocols for specific applications and confirm cross-reactivity in non-human models if required. Overall, the NUDT6 antibody is vital for exploring cellular metabolism, disease mechanisms, and gene regulation pathways.