NDP抗体—艾普蒂

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     Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal liver tissue, Primary antibody: P09065(NDP Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using P09065(NDP Antibody) at dilution 1/20. (Original magnification: ×200)    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P09065(NDP Antibody) at dilution 1/20. (Original magnification: ×200)    

  
  

Neuronal Death Protein (NDP) antibodies are primarily associated with research on neurodegenerative diseases and cellular stress responses. NDP, though not as extensively characterized as other apoptosis-related proteins, is implicated in pathways linked to neuronal cell death, particularly under conditions of oxidative stress, neuroinflammation, or mitochondrial dysfunction. Antibodies targeting NDP are valuable tools in neuroscience research, enabling the detection and localization of NDP in tissues or cultured cells. They help elucidate its role in pathological contexts such as Alzheimer’s disease, Parkinson’s disease, or ischemic brain injury.

NDP antibodies are typically developed using immunogenic peptide sequences derived from conserved regions of the protein. Their specificity is validated through techniques like Western blotting, immunohistochemistry, and knockout cell line controls. Beyond basic research, these antibodies hold potential diagnostic relevance, as altered NDP expression levels in cerebrospinal fluid or blood could serve as biomarkers for neurodegeneration. However, clinical applications remain exploratory, pending further studies to clarify NDP's mechanistic contributions to disease. Current challenges include optimizing antibody sensitivity and cross-reactivity across species. Overall, NDP antibodies represent a niche yet evolving resource for probing molecular pathways in neurological disorders and identifying therapeutic targets.