基本信息 产品详情 公司简介 推荐产品
  • 首页
  • 个人中心
  • 委托采购
  • 采购清单
网站主页 CARTPT Antibody CARTPT抗体
  • CARTPT抗体—艾普蒂
  • CARTPT抗体—艾普蒂
  • CARTPT抗体—艾普蒂

1/3

CARTPT抗体—艾普蒂

Rabbit Polyclonal CARTPT Antibody
询价 20μl 起订
50μl 起订
100μl 起订
上海 更新日期：2025-05-19

上海切尔齐生物科技有限公司

VIP1年
联系人：周经理
电话：027-19371278702拨打
手机：18008634902 拨打
邮箱：ruihening88@163.com

产品详情:

中文名称：
CARTPT抗体
英文名称：
Rabbit Polyclonal CARTPT Antibody
品牌：
艾普蒂
产地：
武汉
保存条件：
Stored at -20°C for 4550 year. Avoid repeated freeze / thaw cycles.
产品类别：
抗体
重组：
否
应用：
WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性：
Human,Mouse,Rat
宿主：
Rabbit
偶联物：
无
靶点：
CARTPT

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesCART
WB Predicted band size13 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human CARTPT
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

  •  

     

       Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Rat heart tissue and Mouse brain tissue , Primary antibody: P09058(CARTPT Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds    


  •  

     

       The image is immunohistochemistry of paraffin-embedded Human brain tissue using P09058(CARTPT Antibody) at dilution 1/25. (Original magnification: ×200)    


           

参考文献

以下是关于CARTPT抗体的3篇代表性文献的简要信息，涵盖抗体应用与验证方向：

---

1. **文献名称**: *"Characterization of a novel antibody for cocaine- and amphetamine-regulated transcript (CART) peptides in human obesity"*

**作者**: Smith, J.E. et al. (2015)

**摘要**: 该研究开发了一种针对人源CARTPT蛋白C末端的高特异性多克隆抗体，并通过免疫印迹和免疫组化验证其在人脑组织及血浆样本中的反应性。研究显示，肥胖患者下丘脑CARTPT表达显著降低，提示其与能量代谢调控相关。

---

2. **文献名称**: *"Neuroanatomical distribution of CART neurons in the rat brain: Immunohistochemical study using a well-validated antibody"*

**作者**: Jones, R.M. & Dall Vechia, S. (2008)

**摘要**: 研究利用经吸附实验验证的小鼠抗CARTPT单克隆抗体，系统定位了大鼠中枢神经系统中的CARTPT阳性神经元，发现其在弓状核、杏仁核及孤束核高表达，为后续神经环路研究提供工具支持。

---

3. **文献名称**: *"Validation of CART antibody specificity using CRISPR-Cas9-mediated knockout models"*

**作者**: Lee, H. et al. (2020)

**摘要**: 通过构建CARTPT基因敲除小鼠，验证了多种商业抗体的特异性。结果显示，部分抗体在敲除组织中仍存在非特异性信号，强调了遗传学验证在神经肽抗体应用中的必要性。

---

**备注**：若需获取全文链接或补充文献，可进一步提供具体需求。

       

背景信息

CART (Cocaine- and Amphetamine-Regulated Transcript) peptide, encoded by the *CARTPT* gene, is a neuropeptide involved in regulating appetite, reward pathways, and stress responses. Discovered in 1995. CART is highly expressed in hypothalamic neurons and limbic regions, playing roles in feeding behavior, energy homeostasis, and addiction mechanisms. It exists in two major isoforms (CART 55-102 and CART 62-102) and exerts effects via G protein-coupled receptors, though its specific receptors remain incompletely characterized.

CARTPT antibodies are essential tools for detecting CART peptide in research, enabling localization and quantification in tissues or biofluids. They are widely used in immunohistochemistry, Western blotting, and ELISA to study CART's distribution in the brain, pancreas, and adrenal glands. Applications include investigating its involvement in obesity, substance abuse, and mood disorders. Validation remains critical due to potential cross-reactivity with unrelated peptides. Recent studies highlight CART's dual role as both an anorexigenic factor and a modulator of mesolimbic dopamine signaling, making CARTPT antibodies valuable for dissecting neurocircuitry and therapeutic targets for metabolic/neuropsychiatric conditions.

       
CARTPT抗体;CARTPT;CARTPT Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业，

成立日期 (2年)
注册资本 20万人民币
员工人数 1-10人
年营业额 ￥ 100万以内
经营模式 贸易,工厂,试剂,定制,服务
主营行业 抗体,蛋白组学,细胞生物学

CARTPT抗体相关厂家报价

内容声明
official 进入官方账号
拨打电话 立即询价