ZFAND5抗体—艾普蒂

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     Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse fat tissue lysate, Primary antibody: P09015(ZFAND5 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P09015(ZFAND5 Antibody) at dilution 1/35. (Original magnification: ×200)    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P09015(ZFAND5 Antibody) at dilution 1/35. (Original magnification: ×200)    

  
  

ZFAND5 (Zinc Finger AN1-Type Domain-Containing Protein 5), also known as ZNF216. is a ubiquitously expressed protein involved in regulating ubiquitin-dependent processes, particularly in cellular stress responses and protein quality control. It contains AN1-type zinc finger domains, which mediate interactions with ubiquitinated proteins and components of the proteasome, suggesting a role in targeting misfolded proteins for degradation. ZFAND5 is implicated in modulating inflammatory signaling pathways, apoptosis, and autophagy, with potential links to neurodegenerative diseases, cancer, and metabolic disorders.

ZFAND5 antibodies are immunological tools designed to detect and quantify ZFAND5 protein expression in various experimental applications, such as Western blotting, immunohistochemistry, immunofluorescence, and co-immunoprecipitation. These antibodies are typically raised in host species like rabbits or mice using immunogenic peptides or recombinant protein fragments. Their specificity is often validated using knockout cell lines or tissues to confirm target recognition. Research utilizing ZFAND5 antibodies has contributed to understanding its molecular functions, including its interplay with the ubiquitin-proteasome system and stress granule dynamics. Such studies highlight ZFAND5's emerging role as a regulatory node in cellular stress adaptation and disease pathogenesis, particularly in contexts of proteotoxic stress and inflammation.