WFDC5抗体—艾普蒂

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     The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P09000(WFDC5 Antibody) at dilution 1/20. (Original magnification: ×200)    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using P09000(WFDC5 Antibody) at dilution 1/20. (Original magnification: ×200)    

  
  

The WFDC5 antibody targets the WFDC5 (WAP Four-Disulfide Core Domain 5) protein, a member of the WFDC family characterized by conserved whey acidic protein (WAP)-type four-disulfide core motifs. WFDC5. also known as HE4 (Human Epididymis Protein 4), is a glycoprotein encoded by the *WFDC2* gene. Initially identified in the epididymis, WFDC5 is expressed in reproductive tissues and has been implicated in sperm maturation and innate immunity due to its potential protease-inhibiting properties.

Recent studies highlight its clinical relevance as a biomarker, particularly in ovarian and endometrial cancers, where elevated WFDC5 levels correlate with disease progression and prognosis. The WFDC5 antibody is widely utilized in research and diagnostics, enabling detection via techniques like immunohistochemistry (IHC), Western blot (WB), and ELISA. Its specificity aids in studying WFDC5's expression patterns, regulatory mechanisms, and interactions in both physiological and pathological contexts. Commercially available monoclonal and polyclonal variants support diverse applications, from basic research exploring reproductive biology to translational studies in oncology. However, cross-reactivity with homologous WFDC proteins remains a consideration, emphasizing the need for validation in experimental settings. Overall, the WFDC5 antibody serves as a critical tool for unraveling the protein's roles in health, disease, and potential therapeutic targeting.